Benzenamine, 2,2'-dithiobis[5-(trifluoromethyl)-

Base Information

• Chemical Name: Benzenamine, 2,2'-dithiobis[5-(trifluoromethyl)-
• CAS No.: 7038-40-6
• Molecular Formula: C14H10F6N2S2
• Molecular Weight: 384.369
• Mol file: 7038-40-6.mol

Synonyms:bis-(2-amino-4-trifluoromethylfenil)disolfuro;2,2'-Diamino-4,4'-di-(trifluormethyl)diphenyldisulfid;2-amino-4-trifluoromethylthiophenol disulfide;bis(2-amino-4-trifluoromethylphenyl) disulfide;

Chemical Property of Benzenamine, 2,2'-dithiobis[5-(trifluoromethyl)-

Chemical Property:

• PSA: 102.64000
• LogP: 6.85040

Purity/Quality:

95% ^*data from raw suppliers

2-Amino-4-trifluoromethylphenylDisulfide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenamine, 2,2'-dithiobis[5-(trifluoromethyl)-

There total 12 articles about Benzenamine, 2,2'-dithiobis[5-(trifluoromethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-amino-5-trifluoromethylbenzothiazole (60388-38-7) → 6,6′-disulfanediylbis(3-(trifluoromethyl)aniline) (7038-40-6)

Guidance literature:

With potassium hydroxide; In isopropyl alcohol;

DOI:10.1016/j.bmcl.2005.12.039

Reference yield: 16.0%

hydrogen sulfide (7783-06-4) + 2-chloro-3-nitro-5-trifluoromethylbenzene (121-17-5) → 6,6′-disulfanediylbis(3-(trifluoromethyl)aniline) (7038-40-6)

Guidance literature:

With ammonium chloride;

Reference yield:

2-amino-4-(trifluoromethyl)benzenethiol hydrochloride (4274-38-8) → 6,6′-disulfanediylbis(3-(trifluoromethyl)aniline) (7038-40-6)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / diethyl ether / 0.17 h / Inert atmosphere; Glovebox; Sonication

2: sodium iodide; iron(III) chloride / acetonitrile / 0.17 h / 20 °C / Inert atmosphere; Glovebox

With iron(III) chloride; triethylamine; sodium iodide; In diethyl ether; acetonitrile;

DOI:10.1021/ic301730z

upstream raw materials:

bis(2-nitro-4-trifluoromethylphenyl) disulfide

2-amino-5-trifluoromethylbenzothiazole

2-chloro-3-nitro-5-trifluoromethylbenzene

2-amino-4-(trifluoromethyl)benzenethiol hydrochloride

Downstream raw materials:

5-(trifluoromethyl)benzo[d]thiazol-2(3H)-one

sulfur

2-mercapto-5-(trifluoromethyl)benzothiazole

1-<5-trifluoro-2-(β,β-dimetossi-α-feniletiltio)fenil>pirrolo

Refernces

• 1、 -. "CONDENSED HETEROCYCLIC COMPOUND HAVING CYCLOALKYLPYRIDYL GROUP OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE INSECTICIDE". . . Retrieved 2018/09/24.
• 2、 Broering, Ellen P.,Dillon, Stephanie,Gale, Eric M.,Steiner, Ramsey A.,Telser, Joshua,Brunold, Thomas C.,Harrop, Todd C.. "Accessing Ni(III)-thiolate versus Ni(II)-thiyl bonding in a family of Ni-N2S2 synthetic models of NiSOD". . p. 3815 - 3828. Retrieved 2015/05/04.