2,2-Dimethyloxirane

Base Information

• Chemical Name: 2,2-Dimethyloxirane
• CAS No.: 558-30-5
• Molecular Formula: C4H8O
• Molecular Weight: 72.1069
• Hs Code.: 29109000
• European Community (EC) Number: 209-193-8
• NSC Number: 24249
• UNII: UJ14MJ1WG0
• DSSTox Substance ID: DTXSID7060330
• Nikkaji Number: J2.669G
• Wikidata: Q71024787
• Metabolomics Workbench ID: 46538
• Mol file: 558-30-5.mol

Synonyms:2-MEP;2-methyl-1,2-epoxypropane

Chemical Property of 2,2-Dimethyloxirane

Chemical Property:

• Appearance/Colour: clear colorless liquid
• Vapor Pressure: 283mmHg at 25°C
• Refractive Index: n20/D 1.374(lit.)
• Boiling Point: 52 °C at 760 mmHg
• Flash Point: 33 °F
• PSA: 12.53000
• Density: 0.871 g/cm³
• LogP: 0.79520
• Storage Temp.: Flammables area
• Sensitive.: Moisture Sensitive
• Solubility.: 58g/l
• Water Solubility.: 58 g/L (20 ºC)
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 72.057514874
• Heavy Atom Count: 5
• Complexity: 47.6

Purity/Quality:

99.0% ^*data from raw suppliers

1,1-Dimethyloxirane ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F,Xi,Xn
• Hazard Codes: F,Xi,Xn,C
• Statements: 11-36/37/38-20/21/22-34
• Safety Statements: 16-26-36-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Plastics & Rubber -> Epoxides
• Canonical SMILES: CC1(CO1)C
• Uses: Isobutylene oxide is an epoxide that is used as an initiator in the synthesis of polyisobutylenes. Isobutylene oxide is employed as an initiator for the preparation of polyisobutylenes. It finds application in the synthesis of 1-tert-butylperoxy-2-methyl-propan-2-ol.

Technology Process of 2,2-Dimethyloxirane

There total 47 articles about 2,2-Dimethyloxirane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

isobutene (115-11-7,15220-85-6) → 2-methyl-1,2-epoxypropane (558-30-5)

Guidance literature:

With methyltrifluoromethyldioxirane; In various solvent(s); for 0.0333333h; other reagent: dimethyldioxirane;

DOI:10.1021/jo981050d

Reference yield: 92.0%

3-chloro-2-methylpropan-2-ol (558-42-9) → 2-methyl-1,2-epoxypropane (558-30-5)

Guidance literature:

With potassium hydroxide; at -15 ℃; for 5h; under 500 Torr;

DOI:10.1039/b004525j

Reference yield: 89.0%

(C4H9)3SnOC(CH3)2CH2Br → 2-methyl-1,2-epoxypropane (558-30-5) + tributyltin bromide (1461-23-0)

Guidance literature:

decompn. at 70°C (0.5 h);

DOI:10.1016/S0022-328X(00)86886-2

upstream raw materials:

diazomethane

acetone

3-chloro-2-methylpropan-2-ol

2-chloro-2-methyl-1-propanol

Downstream raw materials:

2-methyl-1-(piperidin-1-yl)propan-2-ol

3-(piperazin-1-yl)-2-methylpropan-2-ol

1-Methoxy-2-methylpropan-2-ol

2-methoxyisobutanol