(2E)-2,3-diiodoprop-2-en-1-ol

Base Information

• Chemical Name: (2E)-2,3-diiodoprop-2-en-1-ol
• CAS No.: 71264-49-8
• Molecular Formula: C3H4I2O
• Molecular Weight: 309.873
• European Community (EC) Number: 966-134-5
• Nikkaji Number: J1.370.188A
• Mol file: 71264-49-8.mol

Synonyms:(2E)-2,3-diiodoprop-2-en-1-ol;EN300-28244109;71264-49-8

Chemical Property of (2E)-2,3-diiodoprop-2-en-1-ol

Chemical Property:

• XLogP3: 1.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 309.83516
• Heavy Atom Count: 6
• Complexity: 59.8

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C(C(=CI)I)O
• Isomeric SMILES: C(/C(=C\I)/I)O

Technology Process of (2E)-2,3-diiodoprop-2-en-1-ol

There total 1 articles about (2E)-2,3-diiodoprop-2-en-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

propargyl alcohol (107-19-7) → 2,3,3-triiodoallyl alcohol (42778-72-3) + (E)-α,β-diiodoallyl alcohol (71264-49-8)

Guidance literature:

With iodine; In Petroleum ether; for 6h; Ambient temperature;

DOI:10.1016/S0040-4039(01)93713-X

Reference yield: 81.0%

(E)-α,β-diiodoallyl alcohol (71264-49-8) + phenylacetylene (536-74-3) → 5-phenyl-2,4-pentadiyn-1-ol (30353-46-9)

Guidance literature:

With copper(l) iodide; palladium diacetate; triethylamine; In tetrahydrofuran; at 20 ℃; for 18h; Inert atmosphere;

DOI:10.1055/s-0028-1083251

Reference yield: 75.0%

2-ethynyl-benzoic acid methyl ester (33577-99-0) + (E)-α,β-diiodoallyl alcohol (71264-49-8) → methyl 2-(5-hydroxypenta-1,3-diynyl)benzoate (1126638-99-0)

Guidance literature:

With copper(l) iodide; palladium diacetate; triethylamine; In tetrahydrofuran; at 20 ℃; for 7h; Inert atmosphere;

DOI:10.1055/s-0028-1083251

upstream raw materials:

propargyl alcohol

Downstream raw materials:

methyl 2-(5-hydroxypenta-1,3-diynyl)benzoate

5-phenyl-2,4-pentadiyn-1-ol

1,4-diphenyl-1,3-butadiyne