6(1H)-Azulenone, 2,3-dihydro-1,4-dimethyl

Base Information

• Chemical Name: 6(1H)-Azulenone, 2,3-dihydro-1,4-dimethyl
• CAS No.: 71305-89-0
• Molecular Formula: C12H14O
• Molecular Weight: 174.23900
• Mol file: 71305-89-0.mol

Synonyms:

Chemical Property of 6(1H)-Azulenone, 2,3-dihydro-1,4-dimethyl

Chemical Property:

• Melting Point: 98 - 99 °C (diethyl ether)
• PSA: 17.07000
• LogP: 2.40490

Purity/Quality:

99% ^*data from raw suppliers

6(1H)-Azulenone,2,3-dihydro-1,4-dimethyl ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6(1H)-Azulenone, 2,3-dihydro-1,4-dimethyl

There total 2 articles about 6(1H)-Azulenone, 2,3-dihydro-1,4-dimethyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

calamusenone (71305-96-9) → (R)-1,4-Dimethyl-2,3-dihydro-1H-azulen-6-one (71305-89-0,77809-01-9)

Guidance literature:

Multi-step reaction with 2 steps

1: KOH / ethanol / Heating

2: (i) pyrrolidin-2-one hydrotribromide, THF, (ii) DBU, DMSO

With potassium hydroxide; In ethanol;

DOI:10.1016/0031-9422(79)80070-9

Reference yield:

(1R,4R)-1,4-Dimethyl-2,3,4,5,7,8-hexahydro-1H-azulen-6-one (71305-90-3) → (R)-1,4-Dimethyl-2,3-dihydro-1H-azulen-6-one (71305-89-0,77809-01-9)

Guidance literature:

Multistep reaction; (i) pyrrolidin-2-one hydrotribromide, THF, (ii) DBU, DMSO;

DOI:10.1016/0031-9422(79)80070-9

upstream raw materials:

(1R,4R)-1,4-Dimethyl-2,3,4,5,7,8-hexahydro-1H-azulen-6-one

calamusenone