2,3,4,5-Tetrahydro-1,5-benzoxazepine

Base Information

• Chemical Name: 2,3,4,5-Tetrahydro-1,5-benzoxazepine
• CAS No.: 7160-97-6
• Molecular Formula: C9H11NO
• Molecular Weight: 149.192
• Hs Code.: 2934999090
• Mol file: 7160-97-6.mol

Synonyms:1,5-Benzoxazepine,2,3,4,5-tetrahydro;2,3,4,5-tetrahydro-benzo[b][1,4]oxazepine;2,3,4,5-tetrahydrobenz[b][1,4]oxazepine;2,3,4,5-Tetrahydro-benz[b][1,4]oxazepin;HYLJXJSMGIOVIK-UHFFFAOYSA;2,3,4,5-tetrahydrobenzo[b][1,5]oxazepine;

Chemical Property of 2,3,4,5-Tetrahydro-1,5-benzoxazepine

Chemical Property:

• PSA: 21.26000
• LogP: 2.01900

Purity/Quality:

97% ^*data from raw suppliers

2,3,4,5-Tetrahydro-1,5-benzoxazepine 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3,4,5-Tetrahydro-1,5-benzoxazepine

There total 19 articles about 2,3,4,5-Tetrahydro-1,5-benzoxazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,3,4,5-tetrahydro-1,5-benzoxazepin-4-one (704-48-3) → 2,3,4,5-tetrahydro-1,5-benzoxazepine (7160-97-6)

Guidance literature:

2,3,4,5-tetrahydro-1,5-benzoxazepin-4-one; With borane-THF; In tetrahydrofuran; at 70 ℃; for 4h;

With sodium hydroxide; water; In ethyl acetate;

Reference yield: 97.0%

(4E)-2,3-dihydro-4H-chromen-4-one oxime (24541-01-3,535935-39-8) → 2,3,4,5-tetrahydro-1,5-benzoxazepine (7160-97-6)

Guidance literature:

With diisobutylaluminium hydride; In hexane; dichloromethane; at 5 ℃; for 24h; Inert atmosphere;

DOI:10.3390/molecules25061265

Reference yield: 87.0%

chroman-4-one oxime (24541-01-3,535935-39-8) → 2,3,4,5-tetrahydro-1,5-benzoxazepine (7160-97-6)

Guidance literature:

chroman-4-one oxime; With diisobutylaluminium hydride; In hexane; dichloromethane; at 0 - 20 ℃; Inert atmosphere;

With sodium fluoride; In hexane; dichloromethane; water; at 0 ℃; for 0.5h;

DOI:10.3987/COM-08-11629

upstream raw materials:

2-(3-chloro-propylamino)-phenol

3-(3-chloropropyl)-3H-benzooxazol-2-one

chroman-4-one oxime

2,3,4,5-tetrahydro-1,5-benzoxazepin-4-one

Downstream raw materials:

5-(2-chloro-5-nitro-benzoyl)-2,3,4,5-tetrahydro-benzo[b][1,4]oxazepine

5-(3,4-dimethoxy-phenethyl)-2,3,4,5-tetrahydro-benzo[b][1,4]oxazepine

1-(4-Aminobenzoyl)-1,2,3,4-tetrahydro-5,1-benzoxazepine

5-(2-methylamino-5-nitro-benzoyl)-2,3,4,5-tetrahydro-benzo[b][1,4]oxazepine