1-Methoxy-4-phenylnaphthalene

Base Information

• Chemical Name: 1-Methoxy-4-phenylnaphthalene
• CAS No.: 72774-00-6
• Molecular Formula: C17H14O
• Molecular Weight: 234.298
• DSSTox Substance ID: DTXSID40512011
• Nikkaji Number: J1.354.345C
• Wikidata: Q82371081
• Mol file: 72774-00-6.mol

Synonyms:1-Methoxy-4-phenylnaphthalene;72774-00-6;4-METHOXY-1-PHENYLNAPHTHALENE;SCHEMBL1888768;DTXSID40512011;QKXMRCPSMBNBQI-UHFFFAOYSA-N;FT-0712208

Chemical Property of 1-Methoxy-4-phenylnaphthalene

Chemical Property:

• XLogP3: 4.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 234.104465066
• Heavy Atom Count: 18
• Complexity: 256

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC=C(C2=CC=CC=C21)C3=CC=CC=C3

Technology Process of 1-Methoxy-4-phenylnaphthalene

There total 18 articles about 1-Methoxy-4-phenylnaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

C13H15NO4S (1201594-33-3) + phenylboronic acid (98-80-6) → 1-methoxy-4-phenylnaphthalene (72774-00-6)

Guidance literature:

With potassium phosphate; bis(tricyclohexylphosphine)nickel(II) dichloride; In toluene; at 110 ℃; for 24h; Inert atmosphere;

DOI:10.1021/ja906477r

Reference yield: 92.0%

4-methoxynaphthalen-1-yl diethylcarbamate (1201594-02-6) + phenyl(diisobutyl)aluminium (62673-29-4) → 1-methoxy-4-phenylnaphthalene (72774-00-6)

Guidance literature:

With bis(tricyclohexylphosphine)nickel(II) dichloride; In toluene; at 50 ℃; for 24h; Inert atmosphere;

DOI:10.1021/acscatal.7b01058

Reference yield: 92.0%

→ 1-methoxy-4-phenylnaphthalene (72774-00-6)

Guidance literature:

upstream raw materials:

1-chloro-4-methoxynaphthalene

benzene

1-methoxy-4-methylnaphthalene

cyclohexanone

Downstream raw materials:

4-phenyl-1-naphthol