Tylvalosin

Base Information

Chemical Name:Tylvalosin
CAS No.:63409-12-1
Molecular Formula:C₅₃H₈₇NO₁₉
Molecular Weight:1042.27
Hs Code.:
European Community (EC) Number:264-132-2
UNII:9T02S42WQO
DSSTox Substance ID:DTXSID901016510
Wikidata:Q27273124
NCI Thesaurus Code:C152787
Metabolomics Workbench ID:152712
ChEMBL ID:CHEMBL2103834
Mol file:63409-12-1.mol

Synonyms:tylvalosin

Suppliers and Price of Tylvalosin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
Tylvalosin
1 mg
$ 675.00

Medical Isotopes, Inc.
Tylvalosin
10 mg
$ 2400.00

Biorbyt Ltd
Tylvalosin
500 μg
$ 957.10

Biorbyt Ltd
Tylvalosin
100 μg
$ 635.80

Biorbyt Ltd
Tylvalosin
50 μg
$ 425.00

American Custom Chemicals Corporation
TYLVALOSIN 95.00%
25MG
$ 5500.00

American Custom Chemicals Corporation
TYLVALOSIN 95.00%
5MG
$ 2497.39

Total 19 raw suppliers

Chemical Property of Tylvalosin

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:>105°C (dec.)
Boiling Point:1005.4°Cat760mmHg
PKA:13.06±0.70(Predicted)
Flash Point:561.8°C
PSA：250.81000
Density:1.21g/cm³
LogP:4.00130
Storage Temp.:-20°C Freezer, Under Inert Atmosphere
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:3.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:20
Rotatable Bond Count:19
Exact Mass:1041.58722955
Heavy Atom Count:73
Complexity:1860

Purity/Quality:

99%, ^*data from raw suppliers

Tylvalosin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCC1C(C=C(C=CC(=O)C(CC(C(C(C(CC(=O)O1)OC(=O)C)C)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)OC(=O)CC(C)C)(C)O)N(C)C)O)CC=O)C)C)COC4C(C(C(C(O4)C)O)OC)OC
Isomeric SMILES:CC[C@@H]1[C@H](/C=C(/C=C/C(=O)[C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)OC(=O)C)C)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)OC(=O)CC(C)C)(C)O)N(C)C)O)CC=O)C)\C)CO[C@H]4[C@@H]([C@@H]([C@@H]([C@H](O4)C)O)OC)OC
Uses Tylvalosin is an anti-bacterial agent that is shown through study as a good inhibitor of gram-positive bacteria.

Technology Process of Tylvalosin

There total 6 articles about Tylvalosin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 122825-66-5
2',3,4'''-tri-O-acetyl-4''-O-isovaleryltylosin

: 63409-12-1
3-O-acetyl-4-O-isovaleryltylosin

Guidance literature:: With triethylamine; In methanol; at 25 ℃; for 67h;
DOI:10.1039/P19890000787

Reference yield: 45.0%

: 122825-66-5
2',3,4'''-tri-O-acetyl-4''-O-isovaleryltylosin

: 122825-69-8
3-deoxy-4''-O-isovaleryl-3,19-cyclotylosin

: 63409-12-1
3-O-acetyl-4-O-isovaleryltylosin

Guidance literature:: With triethylamine; In methanol; at 25 ℃; for 66h;
DOI:10.1039/P19890000787

Reference yield:

: 1468-39-9
Isovaleric anhydride

: 63409-12-1
3-O-acetyl-4-O-isovaleryltylosin

Guidance literature:: Multi-step reaction with 3 steps

1: 49 percent / 4-dimethylaminopyridine, triethylamine / CH₂Cl₂ / 18 h / 25 °C

2: 82 percent / 4-dimethylaminopyridine, triethylamine / CH₂Cl₂ / 21 h / 25 °C

3: 45 percent / triethylamine (33percent) / methanol / 66 h / 25 °C

With dmap; triethylamine; In methanol; dichloromethane;
DOI:10.1039/P19890000787