2-(4-chlorophenyl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one

Base Information

Chemical Name:2-(4-chlorophenyl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one
CAS No.:73302-12-2
Molecular Formula:C20H15ClN2O
Molecular Weight:334.805
Hs Code.:
DSSTox Substance ID:DTXSID101188820
Nikkaji Number:J2.212.305J

Synonyms:2-(4-chlorophenyl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one;Oprea1_205174;Oprea1_370926;2-(4-chlorophenyl)-3-phenyl-1,2-dihydroquinazolin-4-one;MUKIICNBZDWBNF-UHFFFAOYSA-N;DTXSID101188820;STK060140;AKOS000339732;AKOS022086653;73302-12-2;AO-080/11116333;2,3-dihydro-3-phenyl-2-(4-chlorophenyl)quinazolin-4(1h)-one;2-(4-Chlorophenyl)-2,3-dihydro-3-phenyl-4(1H)-quinazolinone;2-(4-chlorophenyl)-3-phenyl-2,3-dihydro-4(1H)-quinazolinone;2-(4-Chlorophenyl)-3-phenyl-2,3-dihydroquinazoline-4(1H)-one

Suppliers and Price of 2-(4-chlorophenyl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-chlorophenyl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one

Chemical Property:

XLogP3:5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:334.0872908
Heavy Atom Count:24
Complexity:443

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)N2C(NC3=CC=CC=C3C2=O)C4=CC=C(C=C4)Cl

Technology Process of 2-(4-chlorophenyl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one

There total 7 articles about 2-(4-chlorophenyl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 118-48-9
isatoic anhydride

: 104-88-1
4-chlorobenzaldehyde

: 62-53-3
aniline

: 73302-12-2
2-(4-chlorophenyl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one

Guidance literature:: With 732-resin; In ethanol; water; for 2h; Reflux;
DOI:10.1007/s10593-012-1073-4

Reference yield: 94.0%

: 118-48-9
isatoic anhydride

: 62-53-3
aniline

: 873-76-7
para-Chlorobenzyl alcohol

: 73302-12-2
2-(4-chlorophenyl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one

Guidance literature:: isatoic anhydride; aniline; In dimethyl sulfoxide; at 80 ℃; for 0.333333h;

para-Chlorobenzyl alcohol; With hydrogen bromide; In dimethyl sulfoxide; at 80 ℃; for 0.166667h;
DOI:10.1055/s-0036-1591544

Reference yield: 92.0%

: 104-88-1
4-chlorobenzaldehyde

: 4424-17-3
2-aminobenzanilide

: 73302-12-2
2-(4-chlorophenyl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one

Guidance literature:: With silica supported ceric ammonium nitrate (CAN*SiO₂); In acetonitrile; at 20 ℃; for 0.5h;
DOI:10.1016/j.crci.2013.11.008