Eburnamenin-14(15H)-one

Base Information

Chemical Name:Eburnamenin-14(15H)-one
CAS No.:474-00-0
Molecular Formula:C₁₉H₂₂N₂O
Molecular Weight:294.396
Hs Code.:
European Community (EC) Number:207-476-0
UNII:NPD9S131ZU
DSSTox Substance ID:DTXSID701032269
Nikkaji Number:J12.129K
Wikidata:Q27284986
Pharos Ligand ID:UK334WG3GX3R
Metabolomics Workbench ID:123299
ChEMBL ID:CHEMBL1318553
Mol file:474-00-0.mol

Synonyms:(-)-eburnamonine;Cervoxan;eburnamonine;eburnamonine monohydrochloride, (3alpha,16alpha)-isomer;eburnamonine phosphate, (3alpha,16alpha)-isomer;eburnamonine, (3alpha,16alpha)-isomer;vinburnine

Suppliers and Price of Eburnamenin-14(15H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
EBURNAMONINE 95.00%
25G
$ 2000.25

Total 10 raw suppliers

Chemical Property of Eburnamenin-14(15H)-one

Chemical Property:

Vapor Pressure:5.25E-08mmHg at 25°C
Melting Point:174°
Boiling Point:441.9°Cat760mmHg
Flash Point:221°C
PSA：25.24000
Density:1.34g/cm³
LogP:3.71250
XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:294.173213330
Heavy Atom Count:22
Complexity:492

Purity/Quality:

99% ^*data from raw suppliers

EBURNAMONINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(=O)C2
Isomeric SMILES:CC[C@]12CCCN3[C@H]1C4=C(CC3)C5=CC=CC=C5N4C(=O)C2

Technology Process of Eburnamenin-14(15H)-one

There total 56 articles about Eburnamenin-14(15H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 517-30-6
(+) eburnamenine

: 2580-88-3,4880-88-0,53494-54-5,60384-17-0,71697-48-8,474-00-0
(-)-eburnamonine

Guidance literature:: (+) eburnamenine; With hydrogenchloride; In water; at 20 ℃; for 4h; Inert atmosphere;

With pyridinium dichromate; In dichloromethane; water; for 0.5h; Inert atmosphere;
DOI:10.1016/j.chempr.2017.04.007

Reference yield: 84.0%

: 86708-31-8
3-((1R,12bR)-1-Ethyl-1,2,3,4,6,7,12,12b-octahydro-indolo[2,3-a]quinolizin-1-yl)-2-[(E)-hydroxyimino]-propionic acid methyl ester

: 2580-88-3,4880-88-0,53494-54-5,60384-17-0,71697-48-8,474-00-0
(-)-eburnamonine

Guidance literature:: With sodium hydroxide; In water; ethylene glycol; at 155 - 160 ℃; for 3h;

Reference yield: 62.0%

: C₂₀H₂₅N₂O₂⁽¹⁺⁾*ClO₄^(1-)

: 2580-88-3,4880-88-0,53494-54-5,60384-17-0,71697-48-8,474-00-0
(-)-eburnamonine

: 71697-48-8
(–)-20-epi-eburnamonine

Guidance literature:: C₂₀H₂₅N₂O₂⁽¹⁺⁾*ClO₄^(1-); With palladium 10% on activated carbon; hydrogen; In N,N-dimethyl-formamide; at 23 ℃; for 3.5h;

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In N,N-dimethyl-formamide; at 23 ℃; for 3h;
DOI:10.1002/anie.202106184