7-Chloro-2-oxo-1,2-dihydroquinoline-3-carbaldehyde

Base Information

Chemical Name:7-Chloro-2-oxo-1,2-dihydroquinoline-3-carbaldehyde
CAS No.:73568-43-1
Molecular Formula:C10H6ClNO2
Molecular Weight:207.616
Hs Code.:2933499090
European Community (EC) Number:804-030-2
DSSTox Substance ID:DTXSID30501116
Wikidata:Q82353263
Mol file:73568-43-1.mol

Synonyms:73568-43-1;7-chloro-2-hydroxyquinoline-3-carbaldehyde;7-Chloro-2-oxo-1,2-dihydroquinoline-3-carbaldehyde;7-CHLORO-2-OXO-1H-QUINOLINE-3-CARBALDEHYDE;SCHEMBL17603437;DTXSID30501116;YCA56843;MFCD09724101;MFCD09881442;AKOS015949158;AT24323;SB69583;NS-02274;CS-0455283;FT-0762987;7-Chloro-2-hydroxyquinoline-3-carbaldehyde, AldrichCPR

Suppliers and Price of 7-Chloro-2-oxo-1,2-dihydroquinoline-3-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-chloro-2-hydroxyquinoline-3-carbaldehyde
100mg
$ 65.00

SynQuest Laboratories
7-Chloro-2-hydroxyquinoline-3-carbaldehyde
1 g
$ 541.00

Sigma-Aldrich
7-Chloro-2-hydroxyquinoline-3-carbaldehyde Aldrich
1g
$ 277.00

Total 5 raw suppliers

Chemical Property of 7-Chloro-2-oxo-1,2-dihydroquinoline-3-carbaldehyde

Chemical Property:

Vapor Pressure:4.09E-08mmHg at 25°C
Boiling Point:445oC at 760 mmHg
Flash Point:222.9oC
PSA：50.19000
Density:1.497g/cm3
LogP:2.40630
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:207.0087061
Heavy Atom Count:14
Complexity:301

Purity/Quality:

97% ^*data from raw suppliers

7-chloro-2-hydroxyquinoline-3-carbaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22-36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=C1Cl)NC(=O)C(=C2)C=O

Technology Process of 7-Chloro-2-oxo-1,2-dihydroquinoline-3-carbaldehyde

There total 5 articles about 7-Chloro-2-oxo-1,2-dihydroquinoline-3-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 78708-18-6
(E)-N-(3-Chloro-phenyl)-2-formyl-3-hydroxy-acrylamide

: 73568-43-1
7-chloro-2-oxo-1,2-dihydroquinoline-3-carbaldehyde

Guidance literature:: With PPA; at 140 - 150 ℃; for 0.166667h;
DOI:10.1039/P19810001520

Reference yield: 88.0%

: 73568-33-9
2,7-dichloro-quinoline-3-carbaldehyde

: 73568-43-1
7-chloro-2-oxo-1,2-dihydroquinoline-3-carbaldehyde

Guidance literature:: With hydrogenchloride; for 1h; Heating;

Reference yield:

: 588-07-8
3-Chloroacetanilide

: 73568-43-1
7-chloro-2-oxo-1,2-dihydroquinoline-3-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: trichlorophosphate / 0.08 h / 0 - 5 °C

1.2: 8 h / 75 - 80 °C

2.1: acetic acid / water / 4 h / Reflux

With acetic acid; trichlorophosphate; In water; 1.1: Vilsmeier-Haack reaction / 1.2: Vilsmeier-Haack reaction;
DOI:10.1016/j.bmcl.2012.03.100