5-AMINOMETHYL-2-HYDROXY-BENZOIC ACID METHYL ESTER

Base Information

• Chemical Name: 5-AMINOMETHYL-2-HYDROXY-BENZOIC ACID METHYL ESTER
• CAS No.: 7383-01-9
• Molecular Formula: C9H11NO3
• Molecular Weight: 181.191
• Hs Code.: 2922509090
• Mol file: 7383-01-9.mol

Synonyms:5-aminomethyl-salicylic acid methyl ester;5-aminomethyl-2-hydroxybenzoic acid methyl ester;5-Aminomethyl-salicylsaeuremethylester;5-Aminomethyl-2-hydroxy-benzoesaeure-methylester;

Chemical Property of 5-AMINOMETHYL-2-HYDROXY-BENZOIC ACID METHYL ESTER

Chemical Property:

• Vapor Pressure: 0.000277mmHg at 25°C
• Boiling Point: 313oC at 760 mmHg
• Flash Point: 143.1oC
• PSA: 72.55000
• Density: 1.243g/cm3
• LogP: 1.33780
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

97% ^*data from raw suppliers

Methyl5-(aminomethyl)-2-hydroxybenzoate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-AMINOMETHYL-2-HYDROXY-BENZOIC ACID METHYL ESTER

There total 3 articles about 5-AMINOMETHYL-2-HYDROXY-BENZOIC ACID METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

methyl 5-(azidomethyl)-2-(benzyloxy)benzoate (1126794-78-2) → 5-aminomethyl-2-hydroxy-benzoic acid methyl ester (7383-01-9)

Guidance literature:

With hydrogen; palladium on carbon; In methanol; at 25 ℃; for 5h;

Reference yield:

4-Chloromethyl-2-hydroxy-benzoic acid methyl ester → 5-aminomethyl-2-hydroxy-benzoic acid methyl ester (7383-01-9)

Guidance literature:

With diethyl ether; ammonia;

Reference yield:

→ 5-aminomethyl-2-hydroxy-benzoic acid methyl ester (7383-01-9)

Guidance literature:

5-Aminomethyl-salicylsaeure-hydrochlorid, gesaett. methanol. HCl, Siedetemp.;

upstream raw materials:

methyl 5-(azidomethyl)-2-(benzyloxy)benzoate