4-Penten-2-ol, 1-(phenylmethoxy)-, acetate

Base Information

• Chemical Name: 4-Penten-2-ol, 1-(phenylmethoxy)-, acetate
• CAS No.: 742062-16-4
• Molecular Formula: C14H18O3
• Molecular Weight: 234.295
• Mol file: 742062-16-4.mol

Synonyms:

Chemical Property of 4-Penten-2-ol, 1-(phenylmethoxy)-, acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Penten-2-ol, 1-(phenylmethoxy)-, acetate

There total 2 articles about 4-Penten-2-ol, 1-(phenylmethoxy)-, acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-(benzyloxy)-4-penten-2-ol (58931-16-1) + acetic anhydride (108-24-7) → acetic acid 1-benzyloxymethyl-but-3-enyl ester (742062-16-4)

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 20 ℃; for 24h;

DOI:10.1021/jo049556l

Reference yield:

benzyloxyacetoaldehyde (60656-87-3) → acetic acid 1-benzyloxymethyl-but-3-enyl ester (742062-16-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / tetrahydrofuran; diethyl ether / 0.75 h / 0 °C

2: 100 percent / triethylamine; DMAP / CH₂Cl₂ / 24 h / 20 °C

With dmap; triethylamine; In tetrahydrofuran; diethyl ether; dichloromethane;

DOI:10.1021/jo049556l

Reference yield: 70.0%

acetic acid 1-benzyloxymethyl-but-3-enyl ester (742062-16-4) → acetic acid 1-benzyloxymethyl-4-hydroxy-3-oxo-butyl ester

Guidance literature:

With potassium permanganate; acetic acid; In water; acetone; at 20 ℃; for 2h;

DOI:10.1002/ejoc.200500737

upstream raw materials:

1-(benzyloxy)-4-penten-2-ol

acetic anhydride

benzyloxyacetoaldehyde

Downstream raw materials:

(R)-1-benzyloxypent-4-en-2-ol

(2S)-1-(benzyloxy)pent-4-en-2-ol

(R)-1-(benzyloxy)-4-penten-2-yl acetate

Acetic acid (S)-1-benzyloxymethyl-but-3-enyl ester