9-Hexadecyn-1-ol

Base Information

• Chemical Name: 9-Hexadecyn-1-ol
• CAS No.: 88109-73-3
• Molecular Formula: C16H30 O
• Molecular Weight: 238.414
• Hs Code.: 2905290000
• DSSTox Substance ID: DTXSID60236823
• Nikkaji Number: J2.064.541E
• Wikidata: Q83118894
• Mol file: 88109-73-3.mol

Synonyms:9-Hexadecyn-1-ol;88109-73-3;hexadec-9-yn-1-ol;hexadec-9-yn-ol;SCHEMBL21411191;DTXSID60236823;BBJUQSUKHMQMSH-UHFFFAOYSA-N;MFCD00078285;AKOS028108587;FT-0621664

Chemical Property of 9-Hexadecyn-1-ol

Chemical Property:

• Vapor Pressure: 6.27E-06mmHg at 25°C
• Refractive Index: 1.465
• Boiling Point: 339.2oC at 760 mmHg
• PKA: 15.19±0.10(Predicted)
• Flash Point: 145.5oC
• PSA: 20.23000
• Density: 0.871g/cm3
• LogP: 4.68320
• XLogP3: 6.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 11
• Exact Mass: 238.229665576
• Heavy Atom Count: 17
• Complexity: 196

Purity/Quality:

99% ^*data from raw suppliers

9-HEXADECYN-1-OL 95.00% ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCC#CCCCCCCCCO

Technology Process of 9-Hexadecyn-1-ol

There total 21 articles about 9-Hexadecyn-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-tetrahydropyranyloxy-n-9-hexadecyn (25258-24-6) → 9-hexadecyn-1-ol (88109-73-3)

Guidance literature:

With toluene-4-sulfonic acid; at 20 ℃; for 24h;

DOI:10.1002/lipd.12213

Reference yield: 74.0%

9,10-Dibromo-hexadecan-1-ol (93107-76-7) → 9-hexadecyn-1-ol (88109-73-3)

Guidance literature:

With ammonia; sodium amide; In tetrahydrofuran; for 2h;

Reference yield:

C22H44OSi (1256346-67-4) → 9-hexadecyn-1-ol (88109-73-3)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 ℃; for 24h;

DOI:10.1016/j.bmc.2010.08.055

upstream raw materials:

9,10-Dibromo-hexadecan-1-ol

1-tetrahydropyranyloxy-n-9-hexadecyn

hexadec-1-en-9-yne

2-dec-9-ynyloxy-tetrahydro-pyran

Downstream raw materials:

palmitoleyl alcohol

(Z)-9-hexadecenal

hexadec-15-yn-1-ol

Refernces

• 1、 Tasdemir, Deniz,Sanabria, David,Lauinger, Ina L.,Tarun, Alice,Herman, Rob,Perozzo, Remo,Zloh, Mire,Kappe, Stefan H.,Brun, Reto,Carballeira, Néstor M.. "2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage Plasmodium infections". scheme or table. p. 7475 - 7485. Retrieved 2011/01/04.
• 2、 Ishmuratov,Ishmuratova,Odinokov,Tolstikov. "Use of enyne compounds in the synthesis of insect pheromones". . p. 25 - 30. Retrieved 2007/10/03.