1-Phenyl-5-[[(R)-3-(benzyloxy)butyl]sulfonyl]-1H-tetrazole

Base Information

Chemical Name:1-Phenyl-5-[[(R)-3-(benzyloxy)butyl]sulfonyl]-1H-tetrazole
CAS No.:749261-55-0
Molecular Formula:C18H20N4O3S
Molecular Weight:372.448
Hs Code.:
DSSTox Substance ID:DTXSID401174521
Nikkaji Number:J2.296.564F

Synonyms:DTXSID401174521;1-Phenyl-5-[[(R)-3-(benzyloxy)butyl]sulfonyl]-1H-tetrazole;1-Phenyl-5-[[(3R)-3-(phenylmethoxy)butyl]sulfonyl]-1H-tetrazole;749261-55-0

Suppliers and Price of 1-Phenyl-5-[[(R)-3-(benzyloxy)butyl]sulfonyl]-1H-tetrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-Phenyl-5-[[(R)-3-(benzyloxy)butyl]sulfonyl]-1H-tetrazole

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:372.12561169
Heavy Atom Count:26
Complexity:513

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(CCS(=O)(=O)C1=NN=NN1C2=CC=CC=C2)OCC3=CC=CC=C3
Isomeric SMILES:C[C@H](CCS(=O)(=O)C1=NN=NN1C2=CC=CC=C2)OCC3=CC=CC=C3

Technology Process of 1-Phenyl-5-[[(R)-3-(benzyloxy)butyl]sulfonyl]-1H-tetrazole

There total 4 articles about 1-Phenyl-5-[[(R)-3-(benzyloxy)butyl]sulfonyl]-1H-tetrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5-(3-benzyloxy-butylsulfanyl)-1-phenyl-1H-tetrazole

: 749261-55-0
5-[(3R)-3-benzyloxybutane-1-sulfonyl]-1-phenyl-1H-tetrazole

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; for 24h; pH=7.0;
DOI:10.1021/ja0574320

Reference yield:

: 116757-62-1
(R)-3-O-benzyl-1,3-butanediol

: 749261-55-0
5-[(3R)-3-benzyloxybutane-1-sulfonyl]-1-phenyl-1H-tetrazole

Guidance literature:: Multi-step reaction with 3 steps

1: Et₃N; DMAP / CH₂Cl₂ / 8 h

2: K₂CO₃ / acetonitrile / 12 h / 50 °C

3: 1.7 g / m-chlorobenzoic acid / CH₂Cl₂ / 24 h / pH 7.0

With dmap; potassium carbonate; triethylamine; 3-chlorobenzoate; In dichloromethane; acetonitrile;
DOI:10.1021/np049958o

Reference yield:

: 725724-04-9
(R)-3-benzyloxybutyl p-toluenesulfonate

: 749261-55-0
5-[(3R)-3-benzyloxybutane-1-sulfonyl]-1-phenyl-1H-tetrazole

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / acetonitrile / 12 h / 50 °C

2: 1.7 g / m-chlorobenzoic acid / CH₂Cl₂ / 24 h / pH 7.0

With potassium carbonate; 3-chlorobenzoate; In dichloromethane; acetonitrile;
DOI:10.1021/np049958o