Phosphine oxide, (cyclohexylideneethenyl)diphenyl-

Base Information

Chemical Name:Phosphine oxide, (cyclohexylideneethenyl)diphenyl-
CAS No.:7555-01-3
Molecular Formula:C20H21OP
Molecular Weight:308.36
Hs Code.:
DSSTox Substance ID:DTXSID30465941
Nikkaji Number:J2.727.039E

Synonyms:Phosphine oxide, (cyclohexylideneethenyl)diphenyl-;7555-01-3;DTXSID30465941

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Phosphine oxide, (cyclohexylideneethenyl)diphenyl-

Chemical Property:

XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:308.133002287
Heavy Atom Count:22
Complexity:430

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(=C=CP(=O)(C2=CC=CC=C2)C3=CC=CC=C3)CC1

Technology Process of Phosphine oxide, (cyclohexylideneethenyl)diphenyl-

There total 3 articles about Phosphine oxide, (cyclohexylideneethenyl)diphenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 5240-32-4
1-acetoxy-1-ethynyl cyclohexane

: 4559-70-0
Diphenylphosphine oxide

: 7555-01-3
(2-cyclohexylidene-ethenyl)(diphenyl)phosphine oxide

Guidance literature:: With copper(l) iodide; N,N,N,N,-tetramethylethylenediamine; N-ethyl-N,N-diisopropylamine; In ethanol; at 0 - 20 ℃; for 2h; Inert atmosphere; Schlenk technique;
DOI:10.1039/c6cc02563c

Reference yield: 79.0%

: 78-27-3
1-Ethynylcyclohexan-1-ol

: 1079-66-9,74391-44-9
chloro-diphenylphosphine

: 7555-01-3
(2-cyclohexylidene-ethenyl)(diphenyl)phosphine oxide

Guidance literature:: 1-Ethynylcyclohexan-1-ol; chloro-diphenylphosphine; With triethylamine; In diethyl ether; at -12 ℃;

With hydrogenchloride; In diethyl ether; at -12 - 20 ℃;
DOI:10.1080/00397910600639042

Reference yield:

: 78-27-3
1-Ethynylcyclohexan-1-ol

: 7555-01-3
(2-cyclohexylidene-ethenyl)(diphenyl)phosphine oxide

Guidance literature:: Multi-step reaction with 2 steps

1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 0 °C / Inert atmosphere

2: N,N,N,N,-tetramethylethylenediamine; N-ethyl-N,N-diisopropylamine; copper(l) iodide / ethanol / 2 h / 0 - 20 °C / Inert atmosphere; Schlenk technique

With dmap; copper(l) iodide; N,N,N,N,-tetramethylethylenediamine; N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide; In ethanol; dichloromethane;
DOI:10.1039/c6cc02563c