Propanoic acid, 2-(5-(2-chloro-4-(trifluoromethyl)phenoxy)-2-nitrophenoxy)-, ethyl ester, (R)-

Base Information

Chemical Name:Propanoic acid, 2-(5-(2-chloro-4-(trifluoromethyl)phenoxy)-2-nitrophenoxy)-, ethyl ester, (R)-
CAS No.:95181-53-6
Molecular Formula:C₁₈H₁₅ClF₃NO₆
Molecular Weight:433.768
Hs Code.:
Nikkaji Number:J490.833C

Synonyms:RH 4638;Propanoic acid, 2-(5-(2-chloro-4-(trifluoromethyl)phenoxy)-2-nitrophenoxy)-, ethyl ester, (R)-

Suppliers and Price of Propanoic acid, 2-(5-(2-chloro-4-(trifluoromethyl)phenoxy)-2-nitrophenoxy)-, ethyl ester, (R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Propanoic acid, 2-(5-(2-chloro-4-(trifluoromethyl)phenoxy)-2-nitrophenoxy)-, ethyl ester, (R)-

Chemical Property:

Vapor Pressure:2.21E-08mmHg at 25°C
Boiling Point:452.6°Cat760mmHg
Flash Point:227.5°C
Density:1.393g/cm³
XLogP3:5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:7
Exact Mass:433.0539994
Heavy Atom Count:29
Complexity:573

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(C)OC1=C(C=CC(=C1)OC2=C(C=C(C=C2)C(F)(F)F)Cl)[N+](=O)[O-]
Isomeric SMILES:CCOC(=O)[C@@H](C)OC1=C(C=CC(=C1)OC2=C(C=C(C=C2)C(F)(F)F)Cl)[N+](=O)[O-]

Technology Process of Propanoic acid, 2-(5-(2-chloro-4-(trifluoromethyl)phenoxy)-2-nitrophenoxy)-, ethyl ester, (R)-

There total 12 articles about Propanoic acid, 2-(5-(2-chloro-4-(trifluoromethyl)phenoxy)-2-nitrophenoxy)-, ethyl ester, (R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 57057-80-4
ethyl (S)-2-[[(4-methylphenyl)sulfonyl]oxy]propanoate

: Potassium 5-(2-chloro-4-trifluoromethylphenoxy)-2-nitrophenoxide

: 143502-46-9,95181-53-6
RH-4638(R)

Guidance literature:: In acetonitrile; Heating;
DOI:10.1002/ps.2780400404

Reference yield: 52.0%

: 117589-34-1
(-)-ethyl 2-<(p-tolylsulfonyl)oxy>propionate

: Potassium 5-(2-chloro-4-trifluoromethylphenoxy)-2-nitrophenoxide

: 143502-46-9,95181-53-6
RH-4639(S)

Guidance literature:: In acetonitrile; Heating;
DOI:10.1002/ps.2780400404

Reference yield:

: 328-84-7
1,2-dichloro-4-(trifluoromethyl)benzene

: 50594-49-5,143502-46-9,95181-53-6
2-[5-(2-Chloro-4-trifluoromethyl-phenoxy)-2-nitro-phenoxy]-propionic acid ethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) KOH / 1.) DMSO, H₂O, toluene, 2.) 160 deg C, 16 h

2: 88.2 percent / 1 h / 100 °C

3: 50.5 percent / 70percent HNO₃, conc. H₂SO₄ / 1,2-dichloro-ethane / 2 h / 20 °C

4: 97 percent / K₂CO₃ / methanol / 1 h / Heating

5: K₂CO₃ / Heating

With potassium hydroxide; sulfuric acid; nitric acid; potassium carbonate; In methanol; 1,2-dichloro-ethane;
DOI:10.1515/znb-1980-0721