Thioglycine

Base Information

• Chemical Name: Thioglycine
• CAS No.: 758-10-1
• Molecular Formula: C2H5NOS
• Molecular Weight: 91.1338
• UNII: JC58U6NVC2
• DSSTox Substance ID: DTXSID50335011
• Nikkaji Number: J1.245.578J
• Wikidata: Q27104575
• Metabolomics Workbench ID: 52446
• ChEMBL ID: CHEMBL1233056
• Mol file: 758-10-1.mol

Synonyms:thioglycine;Aminothioacetic acid;2-aminoethanethioic S-acid;758-10-1;1-thioglycine;Glycine, thio-;THIOGLYCIN;Amino-monothioessigsaeure;Ethanethioic acid, amino-;alpha-Amino-thioessigsaeure;2-Aminoethanethioic O-acid;JC58U6NVC2;CHEBI:46799;2-Aminoethanethioic S-acid;aminoethanethioic S-acid;UNII-JC58U6NVC2;(Mercaptocarbonyl)methanamine;CHEMBL1233056;DTXSID50335011;AKOS006340362;Q27104575

Chemical Property of Thioglycine

Chemical Property:

• Vapor Pressure: 0.923mmHg at 25°C
• XLogP3: -0.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 91.00918496
• Heavy Atom Count: 5
• Complexity: 44.9

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(=O)S)N

Technology Process of Thioglycine

There total 4 articles about Thioglycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

[(tert-Butoxycarbonyl)amino]ethanethioic S-acid (78212-13-2) → thioglycine (758-10-1)

Guidance literature:

With trifluoroacetic acid; In dichloromethane;

DOI:10.1016/j.bmc.2012.02.028

Reference yield:

1,3-oxazolidine-2,5-dione (2185-00-4) + triethylamine (121-44-8) → thioglycine (758-10-1)

Guidance literature:

With hydrogen sulfide; N,N-dimethyl-formamide;

Reference yield:

H-Gly-SPh (173411-55-7) + triethylamine (121-44-8) → thioglycine (758-10-1)

Guidance literature:

With hydrogen sulfide; benzene;

upstream raw materials:

1,3-oxazolidine-2,5-dione

triethylamine

H-Gly-SPh

hydrogen sulfide

Downstream raw materials:

(thioglycinato-N,S)bis(triphenylphosphane)platinum(II)-chloride

1,3-oxazolidine-2,5-dione