3-Methoxy-6-[4-(3-methylphenyl)-1-piperazinyl]pyridazine

Base Information

• Chemical Name: 3-Methoxy-6-[4-(3-methylphenyl)-1-piperazinyl]pyridazine
• CAS No.: 100241-46-1
• Molecular Formula: C₁₆H₂₀N₄O
• Molecular Weight: 284.361
• UNII: HK76HE61AQ
• DSSTox Substance ID: DTXSID30143050
• Nikkaji Number: J356.371E
• Wikidata: Q27097247
• Metabolomics Workbench ID: 151166
• ChEMBL ID: CHEMBL1233737
• Mol file: 100241-46-1.mol

Synonyms:3-methoxy-6-(4-(3-methylphenyl)-1-piperazinyl)pyridazine;R 61837;R-61837

Chemical Property of 3-Methoxy-6-[4-(3-methylphenyl)-1-piperazinyl]pyridazine

Chemical Property:

• Vapor Pressure: 3.23E-11mmHg at 25°C
• Boiling Point: 527.5°Cat760mmHg
• Flash Point: 272.8°C
• PSA: 41.49000
• Density: 1.166g/cm³
• LogP: 2.25020
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 284.16371127
• Heavy Atom Count: 21
• Complexity: 319

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=CC=C1)N2CCN(CC2)C3=NN=C(C=C3)OC

Technology Process of 3-Methoxy-6-[4-(3-methylphenyl)-1-piperazinyl]pyridazine

There total 2 articles about 3-Methoxy-6-[4-(3-methylphenyl)-1-piperazinyl]pyridazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-chloro-6-[4-(3-methylphenyl)-1-piperazinyl]pyridazine → 3-methoxy-6-[4-(3-methylphenyl)-1-piperazinyl]pyridazine (100241-46-1)

Guidance literature:

With sodium methylate; sodium; In methanol; chloroform; water;

Reference yield:

→ 3-methoxy-6-[4-(3-methylphenyl)-1-piperazinyl]pyridazine (100241-46-1)

Guidance literature: