epicamphor

Base Information

• Chemical Name: epicamphor
• CAS No.: 10292-98-5
• Molecular Formula: C10H16 O
• Molecular Weight: 152.236
• Mol file: 10292-98-5.mol

Synonyms:3-Bornanone,(1S,4S)-(-)- (8CI); Bicyclo[2.2.1]heptan-2-one, 4,7,7-trimethyl-, (1S)-;(-)-Epicamphor; (-)-epi-Camphor; (-)-b-Camphor; Epicamphor; epi-Camphor; b-Camphor

Chemical Property of epicamphor

Chemical Property:

• Vapor Pressure: 0.168mmHg at 25°C
• Melting Point: 186.5°C
• Refractive Index: 1.4752 (estimate)
• Boiling Point: 213°Cat760mmHg
• Flash Point: 69.3°C
• PSA: 17.07000
• Density: 0.982g/cm³
• LogP: 2.40170

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of epicamphor

There total 16 articles about epicamphor which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(-)-bornylene (464-17-5,18383-34-1,2437-75-4) → (1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one (464-49-3,68546-28-1) + epicamphor (10292-98-5)

Guidance literature:

With potassium permanganate; sodium amalgam; mercury(II) diacetate; Multistep reaction; 1)acetic acid,room temp.;2)ether;;

Reference yield:

(1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one (464-49-3,68546-28-1) → epicamphor (10292-98-5)

Guidance literature:

With morpholine; sulfur; at 95 - 97 ℃; for 25h;

Reference yield:

(1R,2S,4R)-2-Chloro-1,7,7-trimethyl-bicyclo[2.2.1]heptane (30462-53-4) → epicamphor (10292-98-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 50 percent / Potassium cyclohexyl oxide / 10 h / Heating; Cyclohexanol as solvent

2: 1)mercuric acetate 2)sodium amalgam 3)potassium permanganate / 1)acetic acid,room temp.;2)ether;

With potassium permanganate; sodium amalgam; mercury(II) diacetate; potassium cyclohexanolate;

upstream raw materials:

(-)-bornylene

2endo-Acetoxy-epicampher

(1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one

sulfuric acid

Downstream raw materials:

p-chlorobenzylidene-2 epicamphre-(-)-(Z)

Refernces

• 1、 Carmack, Marvin,Behforouz, Mohammad,Berchtold, Glenn A.,Berkowitz, Samuel M.,Wiesler, Donald,Barone, Ralph. "The Willgerodt-Kindler Reactions. 6. Isomerization of the Carbonyl Group in Alkanones and Cycloalkanones". . p. 1305 - 1318. Retrieved 2007/10/02.
• 2、 Bondavalli, Francesco,Schenone, Pietro,Ranian, Angelo. "Synthehis of New Amino Derivatives and Carbonyl Transposition in the 1,7,7-Trimethylbicycloheptane Series.". . p. 3256 - 3262. Retrieved 2007/10/02.