2-(3,4-Dihydroxyphenyl)-3,5,7-trimethoxychromen-4-one

Base Information

Chemical Name:2-(3,4-Dihydroxyphenyl)-3,5,7-trimethoxychromen-4-one
CAS No.:7622-61-9
Molecular Formula:C18H16O7
Molecular Weight:344.321
Hs Code.:
DSSTox Substance ID:DTXSID80153149
Nikkaji Number:J1.043.208A
Wikidata:Q83020004

Synonyms:121093-27-4;2-(3,4-Dihydroxyphenyl)-3,5,7-trimethoxychromen-4-one;Quercetin trimethyl ether;Chromen-4-one, 2-(3,4-dihydroxyphenyl)-3,5,7-trimethoxy-;SCHEMBL15635393;DTXSID80153149;3',4'-Dihydroxy-3,5,7-trimethoxyflavone

Suppliers and Price of 2-(3,4-Dihydroxyphenyl)-3,5,7-trimethoxychromen-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(3,4-Dihydroxyphenyl)-3,5,7-trimethoxychromen-4-one

Chemical Property:

Melting Point:282-284 °C (decomp)(Solv: ethanol (64-17-5))
Boiling Point:615.0±55.0 °C(Predicted)
PSA：98.36000
Density:1.45±0.1 g/cm3(Predicted)
LogP:2.89700
XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:344.08960285
Heavy Atom Count:25
Complexity:532

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C(=C1)OC)C(=O)C(=C(O2)C3=CC(=C(C=C3)O)O)OC

Technology Process of 2-(3,4-Dihydroxyphenyl)-3,5,7-trimethoxychromen-4-one

There total 6 articles about 2-(3,4-Dihydroxyphenyl)-3,5,7-trimethoxychromen-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

: 97434-01-0
3,5,7-Trimethoxy-3',4'-diphenylmethylendioxy-flavon

: 7622-61-9
2-(3,4-dihydroxy-phenyl)-3,5,7-trimethoxy-chromen-4-one

Guidance literature:: With acetic acid; In water; at 130 ℃; for 7h;

Reference yield:

: 95626-25-8
2-(3,4-diacetoxy-phenyl)-3,5,7-trimethoxy-chromen-4-one

: 7622-61-9
2-(3,4-dihydroxy-phenyl)-3,5,7-trimethoxy-chromen-4-one

Guidance literature:: With hydrogenchloride; In ethanol; for 1.5h; Heating;
DOI:10.1016/S0031-9422(00)97976-7

Reference yield:

: 2068-02-2
2-(3,4-dihydroxyphenyl)-5-hydroxy-3,7-dimethoxychromen-4-one

: 7622-61-9
2-(3,4-dihydroxy-phenyl)-3,5,7-trimethoxy-chromen-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / 12 h / Ambient temperature

2: K₂CO₃ / acetone / 1 h / Heating

3: 1 M HCl / ethanol / 1.5 h / Heating

With pyridine; hydrogenchloride; potassium carbonate; In ethanol; acetone;
DOI:10.1016/S0031-9422(00)97976-7