3-BUTYLISOQUINOLINE

Base Information

• Chemical Name: 3-BUTYLISOQUINOLINE
• CAS No.: 7661-42-9
• Molecular Formula: C₁₃H₁₅N
• Molecular Weight: 185.269
• Mol file: 7661-42-9.mol

Synonyms:

Chemical Property of 3-BUTYLISOQUINOLINE

Chemical Property:

Purity/Quality:

98.5% ^*data from raw suppliers

3-BUTYLISOQUINOLINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-BUTYLISOQUINOLINE

There total 35 articles about 3-BUTYLISOQUINOLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-(hex-1-yn-1-yl)benzaldehyde (106824-45-7) → 3-n-butylisoquinoline (7661-42-9)

Guidance literature:

With ammonia; In ethanol; at 80 ℃; for 2h;

DOI:10.1248/cpb.48.669

Reference yield: 93.0%

(Z)-2-(2-azidohex-1-enyl)benzaldehyde → 3-n-butylisoquinoline (7661-42-9)

Guidance literature:

With triethyl phosphite; In tetrahydrofuran; at 20 - 35 ℃; for 2h; Inert atmosphere;

DOI:10.1021/acs.joc.7b02831

Reference yield: 77.0%

1-(1-azido-methyl)-2-hex-1-ynyl-benzene (947395-76-8) → 3-n-butylisoquinoline (7661-42-9)

Guidance literature:

With gold(III) chloride; silver hexafluoroantimonate; In tetrahydrofuran; at 100 ℃; for 12h; Inert atmosphere;

DOI:10.1016/j.tetlet.2009.03.129

upstream raw materials:

2-(hex-1-yn-1-yl)benzaldehyde

N-[2-(1-hexynyl)benzyl]-(4-methylbenzyl)sulfonamide

hex-1-yne

2-iodobenzyl alcohol