DIETHYL 2-(2,2,2-TRIFLUOROACETAMIDO)MALONATE

Base Information

• Chemical Name: DIETHYL 2-(2,2,2-TRIFLUOROACETAMIDO)MALONATE
• CAS No.: 76699-09-7
• Molecular Formula: C9H12F3NO5
• Molecular Weight: 271.19000
• Mol file: 76699-09-7.mol

Synonyms:2-(2,2,2-Trifluoro-acetylamino)-malonic acid diethyl ester;Trifluoracetaminomalonsaeure-diaethylester;diethyl trifluoroacetamidomalonate;

Chemical Property of DIETHYL 2-(2,2,2-TRIFLUOROACETAMIDO)MALONATE

Chemical Property:

• PSA: 81.70000
• LogP: 0.55060

Purity/Quality:

99% ^*data from raw suppliers

1,3-Diethyl2-(2,2,2-trifluoroacetamido)propanedioate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1,3-Diethyl 2-(2,2,2-trifluoroacetamido)propanedioate

Technology Process of DIETHYL 2-(2,2,2-TRIFLUOROACETAMIDO)MALONATE

There total 1 articles about DIETHYL 2-(2,2,2-TRIFLUOROACETAMIDO)MALONATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

aminomalonic acid diethyl ester (6829-40-9) + trifluoroacetic anhydride (407-25-0) → trifluoroacetylaminomalonic acid diethyl ester (76699-09-7)

Guidance literature:

In diethyl ether; for 0.166667h; ice-bath;

Reference yield: 82.0%

trifluoroacetylaminomalonic acid diethyl ester (76699-09-7) + 5-(bromomethyl)-2,2-diphenylbenzo[d][1,3]dithiol → diethyl 2-((2,2-diphenylbenzo[d][1,3]dithiol-5-yl)methyl)-2-(2,2,2-trifluoroacetamido)malonate

Guidance literature:

trifluoroacetylaminomalonic acid diethyl ester; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; for 0.333333h;

5-(bromomethyl)-2,2-diphenylbenzo[d][1,3]dithiol; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 6h; Time; Inert atmosphere;

DOI:10.1021/acs.joc.0c02359

Reference yield: 75.0%

trifluoroacetylaminomalonic acid diethyl ester (76699-09-7) + 4-(bromomethyl)-2,2-diphenylbenzo[d][1,3]dithiol → diethyl 2-((2,2-diphenylbenzo[d][1,3]dithiol-4-yl)methyl)-2-(2,2,2-trifluoroacetamido)malonate

Guidance literature:

trifluoroacetylaminomalonic acid diethyl ester; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; for 0.333333h;

4-(bromomethyl)-2,2-diphenylbenzo[d][1,3]dithiol; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 6h; Inert atmosphere;

DOI:10.1021/acs.joc.0c02359

upstream raw materials:

aminomalonic acid diethyl ester

trifluoroacetic anhydride

Downstream raw materials:

(-)-menthyl(Z)-4,4-diethoxycarbonyl-4-trifluoroacetamido-2-butenoate

(-)-menthyl(E)-4,4-diethoxycarbonyl-4-trifluoroacetamido-2-butenoate

(+)-phenylmenthyl(Z)-4,4-diethoxycarbonyl-4-trifluoroacetamido-2-butenoate

(+)-phenylmenthyl(E)-4,4-diethoxycarbonyl-4-trifluoroacetamido-2-butenoate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 76699-09-7 DIETHYL 2-(2,2,2-TRIFLUOROACETAMIDO)MALONATE

Send

Send

Metric Ton KG G Pound L ML

Send

Send