4-(3-Azabicyclo[3.1.0]hexan-1-yl)phenol

Base Information

Chemical Name:4-(3-Azabicyclo[3.1.0]hexan-1-yl)phenol
CAS No.:77062-87-4
Molecular Formula:C11H13NO
Molecular Weight:175.23
Hs Code.:
ChEMBL ID:CHEMBL1192651
DSSTox Substance ID:DTXSID20507980

Synonyms:4-(3-Azabicyclo[3.1.0]hexan-1-yl)phenol;77062-87-4;SCHEMBL4713090;CHEMBL1192651;DTXSID20507980

Suppliers and Price of 4-(3-Azabicyclo[3.1.0]hexan-1-yl)phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(3-Azabicyclo[3.1.0]hexan-1-yl)phenol

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:175.099714038
Heavy Atom Count:13
Complexity:210

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2C1(CNC2)C3=CC=C(C=C3)O

Technology Process of 4-(3-Azabicyclo[3.1.0]hexan-1-yl)phenol

There total 3 articles about 4-(3-Azabicyclo[3.1.0]hexan-1-yl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 66560-12-1
1-(4-hydroxyphenyl)-3-azabicyclo<3.1.0>hexane-3-carboxaldehyde

: 77062-87-4
1-(4-hydroxyphenyl)-3-azybicyclo<3.1.0>hexane

Guidance literature:: With sodium hydroxide; at 100 ℃; for 3h;
DOI:10.1021/jm00137a002

Reference yield:

: 77062-79-4
1-(p-methoxyphenyl)-3-azabicyclo[3.1.0]hexane hydrochloride

: 77062-87-4
1-(4-hydroxyphenyl)-3-azybicyclo<3.1.0>hexane

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / NaH, EtSH / 4 h / Heating

2: 81 percent / 1.25 N aq. NaOH / 3 h / 100 °C

With sodium hydroxide; sodium hydride; ethanethiol;
DOI:10.1021/jm00137a002