2-Chloro-9-(tetrahydropyran-2-yl)adenine

Base Information

Chemical Name:2-Chloro-9-(tetrahydropyran-2-yl)adenine
CAS No.:77111-77-4
Molecular Formula:C10H12ClN5O
Molecular Weight:253.691
Hs Code.:2934999090
DSSTox Substance ID:DTXSID30509617
Mol file:77111-77-4.mol

Synonyms:2-Chloro-9-(tetrahydropyran-2-yl)adenine;77111-77-4;2-CHLORO-9-(TETRAHYDRO-2H-PYRAN-2-YL)-9H-PURIN-6-AMINE;2-CHLORO-9-(OXAN-2-YL)PURIN-6-AMINE;6-Amino-2-chloro-9-tetrahydropyranylpurine;2-Chloro-9-(oxan-2-yl)-9H-purin-6-amine;SCHEMBL243515;DTXSID30509617;IZHATATVLOKVET-UHFFFAOYSA-N;2-Chloro-9-tetrahydropyranyladenine;CDA11177;MFCD12964278;AKOS025402681;WS-01542;CS-0155245;A915340;A1-03332;F1911-3045;2-Chloro-9-(tetrahydro-2H-pyran -2-yl)-9H-purin-6-amine;2-Chloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purin -6-amine;2-CHLORO-9-(TETRAHYDRO-2H-PYRAN-2-YL)-9H-PURINE-6-AMINE

Suppliers and Price of 2-Chloro-9-(tetrahydropyran-2-yl)adenine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-9-(tetrahydropyran-2-yl)adenine
2.5g
$ 1240.00

Medical Isotopes, Inc.
2-Chloro-9-(tetrahydropyran-2-yl)adenine
500 mg
$ 875.00

Matrix Scientific
2-Chloro-9-(tetrahydropyran-2-yl)adenine 95%
5g
$ 1486.00

Crysdot
2-Chloro-9-(tetrahydropyran-2-yl)adenine 95+%
1g
$ 709.00

Ambeed
2-Chloro-9-(tetrahydropyran-2-yl)adenine 95%
250mg
$ 219.00

Ambeed
2-Chloro-9-(tetrahydropyran-2-yl)adenine 95%
1g
$ 546.00

Ambeed
2-Chloro-9-(tetrahydropyran-2-yl)adenine 95%
100mg
$ 111.00

Alichem
2-Chloro-9-(tetrahydropyran-2-yl)adenine
5g
$ 1846.32

Alichem
2-Chloro-9-(tetrahydropyran-2-yl)adenine
1g
$ 751.80

Alichem
2-Chloro-9-(tetrahydropyran-2-yl)adenine
250mg
$ 271.08

Total 6 raw suppliers

Chemical Property of 2-Chloro-9-(tetrahydropyran-2-yl)adenine

Chemical Property:

PSA：78.85000
LogP:2.34220
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
Solubility.:Chloroform, DCM, DMF, Ether
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:253.0730377
Heavy Atom Count:17
Complexity:281

Purity/Quality:

97% ^*data from raw suppliers

2-Chloro-9-(tetrahydropyran-2-yl)adenine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCOC(C1)N2C=NC3=C(N=C(N=C32)Cl)N
Uses 2-Chloro-9-(tetrahydropyran-2-yl)adenine is an intermediate in the synthesis of 2,8-Dihydroxyadenine (D450105), a derivative of adenine which accumulates in 2,8-Dihydroxyadenine Urolithiasis.

Technology Process of 2-Chloro-9-(tetrahydropyran-2-yl)adenine

There total 7 articles about 2-Chloro-9-(tetrahydropyran-2-yl)adenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 20419-68-5
2,6-dichloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine

: 77111-77-4
2-chloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine

Guidance literature:: With ammonia; In methanol; at 80 ℃; for 15h; Sealed tube;

Reference yield: 93.0%

: 110-87-2
3,4-dihydro-2H-pyran

: 5451-40-1
2,6-dichloropurine

: 77111-77-4
2-chloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine

Guidance literature:: 3,4-dihydro-2H-pyran; 2,6-dichloropurine; With toluene-4-sulfonic acid; In ethyl acetate; at 50 ℃; for 1h;

With ammonia; In isopropyl alcohol; at 60 ℃; for 4h; Product distribution / selectivity;

Reference yield:

: 110-87-2
3,4-dihydro-2H-pyran

: 5451-40-1
2,6 dichloropurine

: 77111-77-4
2-chloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine

Guidance literature:: 3,4-dihydro-2H-pyran; 2,6 dichloropurine; toluene-4-sulfonic acid; In ethyl acetate; at 50 ℃;

With ammonia; In isopropyl alcohol; at 60 ℃; for 4h; Inert atmosphere;