N-[3-(4-Hydroxyphenyl)acryloyl]-L-tyrosine

Base Information

Chemical Name:N-[3-(4-Hydroxyphenyl)acryloyl]-L-tyrosine
CAS No.:77201-66-2
Molecular Formula:C₁₈H₁₇NO₅
Molecular Weight:327.337
Hs Code.:
DSSTox Substance ID:DTXSID60708510

Synonyms:SCHEMBL1711585;DTXSID60708510;N-[3-(4-Hydroxyphenyl)acryloyl]-L-tyrosine

Suppliers and Price of N-[3-(4-Hydroxyphenyl)acryloyl]-L-tyrosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Arctom
N-trans-p-Coumaroyltyrosine
10mg
$ 318.00

Total 2 raw suppliers

Chemical Property of N-[3-(4-Hydroxyphenyl)acryloyl]-L-tyrosine

Chemical Property:

Melting Point:137-139°C
PSA：110.35000
LogP:2.76340
XLogP3:1.4
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:327.11067264
Heavy Atom Count:24
Complexity:448

Purity/Quality:

99% ^*data from raw suppliers

N-trans-p-Coumaroyltyrosine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1CC(C(=O)O)NC(=O)C=CC2=CC=C(C=C2)O)O
Isomeric SMILES:C1=CC(=CC=C1C[C@@H](C(=O)O)NC(=O)C=CC2=CC=C(C=C2)O)O
Uses N-p-Coumaroyltyrosine can be used to treat neurodegenerative diseases.

Technology Process of N-[3-(4-Hydroxyphenyl)acryloyl]-L-tyrosine

There total 9 articles about N-[3-(4-Hydroxyphenyl)acryloyl]-L-tyrosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1332371-21-7
N-[4'-hydroxy-(E)-cinnamoyl]-L-tyrosine methyl ester

: 77201-66-2
(-)-N-[4'-dihydroxy-(E)-cinnamoyl]-L-tyrosine

Guidance literature:: N-[4'-hydroxy-(E)-cinnamoyl]-L-tyrosine methyl ester; With lithium hydroxide; In tetrahydrofuran; water; at 45 ℃; for 6h; Inert atmosphere;

In tetrahydrofuran; water; Inert atmosphere;
DOI:10.1016/j.bmc.2018.04.044