Chlorosulfuric acid, 4-methylphenyl ester

Base Information

• Chemical Name: Chlorosulfuric acid, 4-methylphenyl ester
• CAS No.: 772-80-5
• Molecular Formula: C7H7ClO3S
• Molecular Weight: 206.65
• Mol file: 772-80-5.mol

Synonyms:

Chemical Property of Chlorosulfuric acid, 4-methylphenyl ester

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Chlorosulfuric acid, 4-methylphenyl ester

There total 3 articles about Chlorosulfuric acid, 4-methylphenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

p-cresol (106-44-5) → 4-methylphenyl chlorosulfate (772-80-5)

Guidance literature:

With pyridine; sulfuryl dichloride; In diethyl ether; at -78 - 20 ℃; for 2h; Inert atmosphere;

DOI:10.1021/ja405949a

Reference yield:

sodium 4-methylphenoxide (1121-70-6) → 4-methylphenyl chlorosulfate (772-80-5)

Guidance literature:

With sulfuryl dichloride; benzene; at 0 - 5 ℃;

Reference yield:

→ 4-methylphenyl chlorosulfate (772-80-5)

Guidance literature:

p-Kresol 1, SO2Cl2, Ether , Pyridin;

upstream raw materials:

sodium 4-methylphenoxide

p-cresol

Downstream raw materials:

di-tert-butyl dicarbonate

Refernces

• 1、 Debergh, J. Robb,Niljianskul, Nootaree,Buchwald, Stephen L.. "Synthesis of aryl sulfonamides via palladium-catalyzed chlorosulfonylation of arylboronic acids". supporting information. p. 10638 - 10641. Retrieved 2013/08/23.