3-Ethynyl-6-methylpyridazine

Base Information

Chemical Name:3-Ethynyl-6-methylpyridazine
CAS No.:77778-20-2
Molecular Formula:C7H6N2
Molecular Weight:118.13600
Hs Code.:
DSSTox Substance ID:DTXSID70517610
Wikidata:Q82379724

Synonyms:3-ethynyl-6-methylpyridazine;77778-20-2;3-Ethynyl-6-methyl-pyridazine;Pyridazine, 3-ethynyl-6-methyl-;SCHEMBL3721845;DTXSID70517610;QEDQKQRYAKDYOW-UHFFFAOYSA-N;AKOS026718981;BS-46820;CS-0158548;E74776;EN300-787682;F2167-2845

Suppliers and Price of 3-Ethynyl-6-methylpyridazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Activate Scientific
3-Ethynyl-6-methyl-pyridazine 95%
100 mg
$ 351.00

Total 3 raw suppliers

Chemical Property of 3-Ethynyl-6-methylpyridazine

Chemical Property:

PSA：25.78000
LogP:0.76630
XLogP3:0.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:118.053098200
Heavy Atom Count:9
Complexity:133

Purity/Quality:

97% ^*data from raw suppliers

3-Ethynyl-6-methyl-pyridazine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NN=C(C=C1)C#C

Technology Process of 3-Ethynyl-6-methylpyridazine

There total 2 articles about 3-Ethynyl-6-methylpyridazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 86521-12-2
3-Methyl-6-trimethylsilanylethynyl-pyridazine

: 77778-20-2
3-ethynyl-6-methylpyridazine

Guidance literature:: With potassium hydroxide; In methanol; for 1h; Ambient temperature;
DOI:10.1055/s-1983-30319

Reference yield:

: 1121-79-5
3-chloro-6-methylpyridazine

: 77778-20-2
3-ethynyl-6-methylpyridazine

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / bispalladium dichloride, copper(I) iodide, triethylamine / 6 h / 100 °C

2: 76 percent / aq. KOH / methanol / 1 h / Ambient temperature

With bis-triphenylphosphine-palladium(II) chloride; potassium hydroxide; copper(l) iodide; triethylamine; In methanol;
DOI:10.1055/s-1983-30319

Reference yield: 52.0%

: 624-38-4,1032416-46-8
para-diiodobenzene

: 77778-20-2
3-ethynyl-6-methylpyridazine

: 1233845-64-1
3-((4-iodophenyl)ethynyl)-6-methylpyridazine

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In tetrahydrofuran; at 20 ℃; for 48h; Inert atmosphere;
DOI:10.3987/COM-10-11934