Benzenedodecanoic acid, 4-(2-phenylethenyl)-, (E)-

Base Information

• Chemical Name: Benzenedodecanoic acid, 4-(2-phenylethenyl)-, (E)-
• CAS No.: 77814-49-4
• Molecular Formula: C26H34O2
• Molecular Weight: 378.555
• Mol file: 77814-49-4.mol

Synonyms:

Chemical Property of Benzenedodecanoic acid, 4-(2-phenylethenyl)-, (E)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenedodecanoic acid, 4-(2-phenylethenyl)-, (E)-

There total 10 articles about Benzenedodecanoic acid, 4-(2-phenylethenyl)-, (E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

12-[4-((E)-Styryl)-phenyl]-dodecanoic acid methyl ester (91202-48-1) → 12-[4-((E)-Styryl)-phenyl]-dodecanoic acid (77814-49-4)

Guidance literature:

With potassium hydroxide; In water; acetone; Heating;

DOI:10.1021/ja00401a053

Reference yield:

1-(4-methylphenyl)cyclododecene (91202-38-9) → 12-[4-((E)-Styryl)-phenyl]-dodecanoic acid (77814-49-4)

Guidance literature:

Multi-step reaction with 5 steps

1: 1.) O₃; 2.) sulfuric acid / 1.) 20 min; 2.) 30 min, reflux

2: 48 percent / N-bromosuccinimide / CHCl₃ / 0.33 h / Heating; Irradiation

3: 1.) triphenylphosphine; 2.) potassium carbonate / 1.) xylene, reflux, 1 h; 2.) methylene chloride, tetrahydrofuran, reflux

4: 22 percent / ZnHg, 25 percent hydrochloric acid / toluene / Heating

5: potassium hydroxide / H₂O; acetone / 2 h / Heating

With hydrogenchloride; potassium hydroxide; N-Bromosuccinimide; sulfuric acid; potassium carbonate; ozone; triphenylphosphine; mercury; zinc; In chloroform; water; acetone; toluene;

DOI:10.1021/ja00331a041

Reference yield:

cyclododecanone (830-13-7) → 12-[4-((E)-Styryl)-phenyl]-dodecanoic acid (77814-49-4)

Guidance literature:

Multi-step reaction with 6 steps

1: 1.) magnesium; 2.) toluenesulfonic acid / 1.) tetrahydrofuran, reflux, 2.5 h; 2.) toluene

2: 1.) O₃; 2.) sulfuric acid / 1.) 20 min; 2.) 30 min, reflux

3: 48 percent / N-bromosuccinimide / CHCl₃ / 0.33 h / Heating; Irradiation

4: 1.) triphenylphosphine; 2.) potassium carbonate / 1.) xylene, reflux, 1 h; 2.) methylene chloride, tetrahydrofuran, reflux

5: 22 percent / ZnHg, 25 percent hydrochloric acid / toluene / Heating

6: potassium hydroxide / H₂O; acetone / 2 h / Heating

With hydrogenchloride; potassium hydroxide; N-Bromosuccinimide; sulfuric acid; o-toluenesulfonic acid; potassium carbonate; ozone; magnesium; triphenylphosphine; mercury; zinc; In chloroform; water; acetone; toluene;

DOI:10.1021/ja00331a041

upstream raw materials:

12-[4-((E)-Styryl)-phenyl]-dodecanoic acid methyl ester

para-bromotoluene

1-(4-methylphenyl)cyclododecene

12-Oxo-12-p-tolyl-dodecanoic acid methyl ester