Benzo[b]thiophene, 2-(1-naphthalenyl)-

Base Information

• Chemical Name: Benzo[b]thiophene, 2-(1-naphthalenyl)-
• CAS No.: 78176-92-8
• Molecular Formula: C₁₈H₁₂S
• Molecular Weight: 260.359
• Mol file: 78176-92-8.mol

Synonyms:

Chemical Property of Benzo[b]thiophene, 2-(1-naphthalenyl)-

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzo[b]thiophene, 2-(1-naphthalenyl)-

There total 20 articles about Benzo[b]thiophene, 2-(1-naphthalenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-(1,3-dimethoxy-1,3-dioxopropan-2-yl)-4-(benzo[b]thiophen-2-yl)-1,2-dihydronaphthalene → 2-(naphthalen-1-yl)benzo[b]thiophene (78176-92-8)

Guidance literature:

With gallium(III) trichloride; In dichloromethane; at 40 ℃; for 0.5h; Inert atmosphere;

DOI:10.1021/acs.joc.7b00209

Reference yield: 93.0%

methyl(2-(2-(naphthalen-1-yl)ethynyl)phenyl)sulfane (1170724-05-6) → 2-(naphthalen-1-yl)benzo[b]thiophene (78176-92-8)

Guidance literature:

With toluene-4-sulfonic acid; In ethanol; at 160 ℃; for 2h; Microwave irradiation;

DOI:10.1016/j.tetlet.2009.03.087

Reference yield: 92.0%

benzo[b]thiophen-2-yl triethylsilane + 1-Bromonaphthalene (90-11-9) → 2-(naphthalen-1-yl)benzo[b]thiophene (78176-92-8)

Guidance literature:

With copper (II)-fluoride; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tris(2,4,6-trimethoxyphenyl)phosphine; cesium fluoride; at 100 ℃; for 17h; Inert atmosphere; Glovebox;

DOI:10.1002/anie.201712081

upstream raw materials:

(dihydro-3',4' naphtyl-1')-2 benzothiophene

1-Bromonaphthalene

Benzo[b]thiophene

3,4-dihydronaphthalene-1(2H)-one