2-Fluoro-3,6-dimethoxybenzaldehyde

Base Information

Chemical Name:2-Fluoro-3,6-dimethoxybenzaldehyde
CAS No.:783342-33-6
Molecular Formula:C9H9FO3
Molecular Weight:184.167
Hs Code.:
DSSTox Substance ID:DTXSID50442032
Wikidata:Q82259089
Mol file:783342-33-6.mol

Synonyms:2-FLUORO-3,6-DIMETHOXYBENZALDEHYDE;783342-33-6;3,6-Dimethoxy-2-fluorobenzaldehyde;Benzaldehyde, 2-fluoro-3,6-dimethoxy-;SCHEMBL1478225;DTXSID50442032;LNPHQRXMWZSAHH-UHFFFAOYSA-N;MFCD19439911;CS-0131632;E91855

Suppliers and Price of 2-Fluoro-3,6-dimethoxybenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3,6-Dimethoxy-2-fluorobenzaldehyde
10mg
$ 45.00

TRC
3,6-Dimethoxy-2-fluorobenzaldehyde
100mg
$ 200.00

Crysdot
2-Fluoro-3,6-dimethoxybenzaldehyde 95+%
1g
$ 353.00

AOBChem
3,6-Dimethoxy-2-fluorobenzaldehyde 95%
1g
$ 269.00

AOBChem
3,6-Dimethoxy-2-fluorobenzaldehyde 95%
500mg
$ 192.00

AOBChem
3,6-Dimethoxy-2-fluorobenzaldehyde 95%
25g
$ 3214.00

AOBChem
3,6-Dimethoxy-2-fluorobenzaldehyde 96%
10g
$ 1636.00

AOBChem
3,6-Dimethoxy-2-fluorobenzaldehyde 95%
5g
$ 962.00

American Custom Chemicals Corporation
2-FLUORO-3,6-DIMETHOXYBENZALDEHYDE 95.00%
5MG
$ 496.61

Total 8 raw suppliers

Chemical Property of 2-Fluoro-3,6-dimethoxybenzaldehyde

Chemical Property:

PSA：35.53000
LogP:1.65540
XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:184.05357231
Heavy Atom Count:13
Complexity:174

Purity/Quality:

97% ^*data from raw suppliers

3,6-Dimethoxy-2-fluorobenzaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C(=C(C=C1)OC)F)C=O

Technology Process of 2-Fluoro-3,6-dimethoxybenzaldehyde

There total 2 articles about 2-Fluoro-3,6-dimethoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 82830-49-7
2-fluoro-1,4-dimethoxybenzene

: 783342-33-6
2-fluoro-3,6-dimethoxybenzaldehyde

Guidance literature:: 2-fluoro-1,4-dimethoxybenzene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

N,N-dimethyl-formamide; In tetrahydrofuran; hexane; at -70 ℃; for 3h;

With acetic acid; In tetrahydrofuran; hexane; at -78 ℃;

Reference yield:

: 150-78-7
1,4-dimethoxybezene

: 783342-33-6
2-fluoro-3,6-dimethoxybenzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) nBuLi, 2.) N-fluorobenzenesulfonimide / 1.) THF, RT, 1 h, 2.) THF, from -60 deg C to RT, overnight

2: 1.) BuLi / 1.) hexane, THF, -65 degC, 0.5 h, 2.) hexane, THF, from -65 deg C to RT

With n-butyllithium; N-fluorobis(benzenesulfon)imide;
DOI:10.1021/jm950639r