Methyl (2R)-2-aminononanoate

Base Information

• Chemical Name: Methyl (2R)-2-aminononanoate
• CAS No.: 78342-51-5
• Molecular Formula: C10H21NO2
• Molecular Weight: 187.282
• DSSTox Substance ID: DTXSID801309255
• Mol file: 78342-51-5.mol

Synonyms:78342-51-5;Methyl (2R)-2-aminononanoate;Methyl (R)-2-aminononanoate;DTXSID801309255

Chemical Property of Methyl (2R)-2-aminononanoate

Chemical Property:

• XLogP3: 2.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 8
• Exact Mass: 187.157228913
• Heavy Atom Count: 13
• Complexity: 137

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCC(C(=O)OC)N
• Isomeric SMILES: CCCCCCC[C@H](C(=O)OC)N

Technology Process of Methyl (2R)-2-aminononanoate

There total 3 articles about Methyl (2R)-2-aminononanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S,5R)-2-(3,4-Dimethoxy-benzyl)-5-heptyl-3,6-dimethoxy-2-methyl-2,5-dihydro-pyrazine (81136-59-6) → (S)-2-Amino-nonanoic acid methyl ester (78342-51-5) + (R)-2-Amino-nonanoic acid methyl ester (78342-51-5) + (S)-2-amino-3-(3,4-dimethoxyphenyl)-2-methylpropanoic acid methyl ester (19728-71-3)

Guidance literature:

With hydrogenchloride; for 4h; Yield given; Ambient temperature;

Reference yield:

(2S,5R)-2-(3,4-Dimethoxy-benzyl)-5-heptyl-3,6-dimethoxy-2-methyl-2,5-dihydro-pyrazine (81136-59-6) → (S)-2-Amino-nonanoic acid methyl ester (78342-51-5) + (R)-2-Amino-nonanoic acid methyl ester (78342-51-5) + (S)-2-amino-3-(3,4-dimethoxyphenyl)-2-methylpropanoic acid methyl ester (19728-71-3)

Guidance literature:

With hydrogenchloride; for 4h; Yield given; Ambient temperature;

Reference yield:

(2S,5R)-2-tert-Butyl-5-heptyl-3,6-dimethoxy-2,5-dihydro-pyrazine (84907-95-9) → (S)-2-amino-3,3-dimethyl-butyric acid methyl ester (63038-26-6) + (R)-2-Amino-nonanoic acid methyl ester (78342-51-5)

Guidance literature:

With hydrogenchloride; ammonium hydroxide; Yield given. Multistep reaction; 1.) room temp., 48 h, 2.) H₂O, ether, pH=8-10;

upstream raw materials:

(2S,5R)-2-(3,4-Dimethoxy-benzyl)-5-heptyl-3,6-dimethoxy-2-methyl-2,5-dihydro-pyrazine

(2S,5R)-2-tert-Butyl-5-heptyl-3,6-dimethoxy-2,5-dihydro-pyrazine

Downstream raw materials:

(R)-2-aminononanoic acid