N-(1,3-benzothiazol-2-yl)-2-fluorobenzamide

Base Information

Chemical Name:N-(1,3-benzothiazol-2-yl)-2-fluorobenzamide
CAS No.:79091-17-1
Molecular Formula:C14H9FN2OS
Molecular Weight:272.303
Hs Code.:
European Community (EC) Number:665-130-8

Synonyms:N-(1,3-benzothiazol-2-yl)-2-fluorobenzamide;Cambridge id 5133891;Oprea1_382628;Oprea1_497559;SCHEMBL4918642;STK052983;AKOS001648192;CCG-276026;EU-0076539;AB00074247-01;SR-01000478215;SR-01000478215-1

Suppliers and Price of N-(1,3-benzothiazol-2-yl)-2-fluorobenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(1,3-benzothiazol-2-yl)-2-fluorobenzamide

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:272.04196225
Heavy Atom Count:19
Complexity:341

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(=O)NC2=NC3=CC=CC=C3S2)F

Technology Process of N-(1,3-benzothiazol-2-yl)-2-fluorobenzamide

There total 2 articles about N-(1,3-benzothiazol-2-yl)-2-fluorobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.6%

: 136-95-8,102337-98-4,84293-42-5
2-amino-benzthiazole

: 445-29-4
o-fluoro-benzoic acid

: 79091-17-1
N?(1,3?benzothiazol?2?yl)?2?fluorobenzamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 0 - 20 ℃;
DOI:10.1007/s11696-021-01730-8

Reference yield: 76.0%

: 136-95-8,102337-98-4,84293-42-5
2-amino-benzthiazole

: 393-52-2
2-Fluorobenzoyl chloride

: 79091-17-1
N?(1,3?benzothiazol?2?yl)?2?fluorobenzamide

Guidance literature:: With triethylamine; In benzene; 1.) r.t., 1 h, 2.) reflux, 0.5 h;

Reference yield:

: 79091-17-1
N?(1,3?benzothiazol?2?yl)?2?fluorobenzamide

: 35242-42-3
1,4-dihydro-phenylquinazolin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 45 percent / 0.08 h / Heating

2: Raney nickel / ethanol / 6 h / Heating

With nickel; In ethanol;