3-(3-Hydroxypropynyl)-benzylamine

Base Information

Chemical Name:3-(3-Hydroxypropynyl)-benzylamine
CAS No.:793695-91-7
Molecular Formula:C10H11NO
Molecular Weight:161.203
Hs Code.:
DSSTox Substance ID:DTXSID801280790

Synonyms:793695-91-7;3-(3-Hydroxypropynyl)-benzylamine;SCHEMBL3731068;JZQFSQRVZXRYAR-UHFFFAOYSA-N;DTXSID801280790;AKOS006291578;3-(3-(Aminomethyl)phenyl)prop-2-yn-1-ol;3-[3-(Aminomethyl)phenyl]-2-propyn-1-ol;F2167-5499

Suppliers and Price of 3-(3-Hydroxypropynyl)-benzylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 3-(3-Hydroxypropynyl)-benzylamine

Chemical Property:

XLogP3:0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:161.084063974
Heavy Atom Count:12
Complexity:189

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)C#CCO)CN

Technology Process of 3-(3-Hydroxypropynyl)-benzylamine

There total 1 articles about 3-(3-Hydroxypropynyl)-benzylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 696-40-2
3-iodobenzylamine

: 107-19-7
propargyl alcohol

: 793695-91-7
3-(3-hydroxypropynyl)benzylamine

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine; at 20 ℃; for 3h;
DOI:10.1021/jm049580r

Reference yield:

: 793695-91-7
3-(3-hydroxypropynyl)benzylamine

: 793695-60-0
ethyl (1'S,2'R,3'S,4'R,5'S)-4'-(2,6-dichloropurin-9-yl)-2',3'-O-(isopropylidene)bicyclo[3.1.0]hexane-1'-carboxylate

: 793695-73-5
(1'S,2'R,3'S,4'R,5'S)-4'-[6-(3-(3-hydroxypropynyl)benzylamino)-2-chloropurin-9-yl]-2',3'-O-isopropylidenebicyclo[3.1.0]haxane-1'-carboxylic acid ethyl ester

Guidance literature:: With triethylamine; In methanol; at 20 ℃; for 3h;
DOI:10.1021/jm049580r

Reference yield:

: 793695-91-7
3-(3-hydroxypropynyl)benzylamine

: (1'S,2'R,3'S,4'R,5'S)-4'-[6-(3-(3-hydroxypropynyl)benzylamino)-2-chloropurin-9-yl]-2',3'-dihydroxybicyclo[3.1.0]hexane-1'-carboxylic acid methylamide

Guidance literature:: Multi-step reaction with 3 steps

1: Et₃N / methanol / 3 h / 20 °C

2: methanol; H₂O / 20 °C

3: aq. TFA / methanol / 3 h / 70 °C

With triethylamine; trifluoroacetic acid; In methanol; water;
DOI:10.1021/jm049580r