(±)-Norketamine HCl

Base Information

Chemical Name:(±)-Norketamine HCl
CAS No.:79499-59-5
Molecular Formula:C12H14ClNO.ClH
Molecular Weight:260.163
Hs Code.:
Mol file:79499-59-5.mol

Synonyms:Cyclohexanone,2-amino-2-(2-chlorophenyl)-,hydrochloride;2-AMINO-2-(2-CHLOROPHENYL)CYCLOHEXANONE HCL;

Suppliers and Price of (±)-Norketamine HCl

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(±)-Norketamine hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
1 mL
$ 32.70

Sigma-Aldrich
(±)-Norketamine hydrochloride solution
036-1ml
$ 31.70

Cayman Chemical
Norketamine (hydrochloride) ≥98%
5mg
$ 108.00

Cayman Chemical
Norketamine (hydrochloride) (CRM)
1mg
$ 30.00

Cayman Chemical
Norketamine (hydrochloride) ≥98%
1mg
$ 28.00

Total 3 raw suppliers

Chemical Property of (±)-Norketamine HCl

Chemical Property:

Flash Point:9℃
PSA：43.09000
LogP:4.13940
Storage Temp.:?20°C

Purity/Quality:

99% ^*data from raw suppliers

(±)-Norketamine hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:F,T
Statements: 11-23/24/25-39/23/24/25
Safety Statements: 7-16-36/37-45

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (±)-Norketamine HCl

There total 3 articles about (±)-Norketamine HCl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: (±)-2-(2-chlorophenyl)-2-hydroxycyclohexan-1-one

: 79499-59-5
2-Amino-2-(2-chlorophenyl)cyclohexanone hydrochloride

Guidance literature:: (±)-2-(2-chlorophenyl)-2-hydroxycyclohexan-1-one; With methanesulfonyl chloride; triethylamine; In tetrahydrofuran; at -5 - 0 ℃; for 1h; Inert atmosphere;

With ammonia; In methanol; at 15 - 20 ℃;
DOI:10.1021/acs.joc.0c01090

Reference yield:

: 6740-85-8
(2-chlorophenyl)(cyclopentyl)methanone

: 79499-59-5
2-Amino-2-(2-chlorophenyl)cyclohexanone hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethyl phosphite; potassium hydroxide; oxygen / ethanol / 48 h / 30 °C

2.1: triethylamine; methanesulfonyl chloride / tetrahydrofuran / 1 h / -5 - 0 °C / Inert atmosphere

2.2: 15 - 20 °C

With oxygen; methanesulfonyl chloride; triethylamine; potassium hydroxide; triethyl phosphite; In tetrahydrofuran; ethanol;
DOI:10.1021/acs.joc.0c01090