2,4-Dimethyl-6-(2-phenylethyl)pyridine

Base Information

• Chemical Name: 2,4-Dimethyl-6-(2-phenylethyl)pyridine
• CAS No.: 79560-51-3
• Molecular Formula: C15H17N
• Molecular Weight: 211.307
• DSSTox Substance ID: DTXSID70508407
• Wikidata: Q82365293
• Mol file: 79560-51-3.mol

Synonyms:2,4-Dimethyl-6-(2-phenylethyl)pyridine;79560-51-3;DTXSID70508407

Chemical Property of 2,4-Dimethyl-6-(2-phenylethyl)pyridine

Chemical Property:

• XLogP3: 3.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 211.136099547
• Heavy Atom Count: 16
• Complexity: 196

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=NC(=C1)CCC2=CC=CC=C2)C

Technology Process of 2,4-Dimethyl-6-(2-phenylethyl)pyridine

There total 5 articles about 2,4-Dimethyl-6-(2-phenylethyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + 2,4-lutidine (108-47-4) → (phenyl-2' ethyl)-2 dimethyl-4,6 pyridine (79560-51-3)

Guidance literature:

With tris(pentafluorophenyl)borate; C₄₂H₅₁N₃PSc; In chlorobenzene; at 100 ℃; for 7h; Inert atmosphere; Schlenk technique; Glovebox;

DOI:10.1002/aoc.6345

Reference yield:

2,4,6-trimethyl-pyridine (108-75-8) + benzyl chloride (100-44-7) → (phenyl-2' ethyl)-2 dimethyl-4,6 pyridine (79560-51-3)

Guidance literature:

With phenyllithium; In diethyl ether; at 21 ℃; for 2.5h;

Reference yield:

2,4,6-trimethyl-pyridine (108-75-8) + benzyl chloride (100-44-7) → (phenyl-2' ethyl)-4 dimethyl-2,6 pyridine (36917-44-9) + (phenyl-2' ethyl)-2 dimethyl-4,6 pyridine (79560-51-3)

Guidance literature:

With phenyllithium; In tetrahydrofuran; at 23 ℃; for 23h; Product distribution; further deprotonating agent, solvents, temperature, time;

upstream raw materials:

2,4,6-trimethyl-pyridine

benzyl chloride

styrene

2,4-lutidine