2-(2,4-DICHLORO-PHENYL)-5-METHYL-2,4-DIHYDRO-[1,2,4]TRIAZOL-3-ONE

Base Information

• Chemical Name: 2-(2,4-DICHLORO-PHENYL)-5-METHYL-2,4-DIHYDRO-[1,2,4]TRIAZOL-3-ONE
• CAS No.: 79604-49-2
• Molecular Formula: C9H7Cl2N3O
• Molecular Weight: 244.08
• Mol file: 79604-49-2.mol

Synonyms:4,5-dihydro-1-(2,4-dichlorophenyl)-3-methyl-1,2,4-triazol-5(1H)-one;1-(2,4-dichlorophenyl)-3-methyl-1,2,4-triazolin-5-one;1-(2,4-dichlorophenyl)-3-methyl-1H-1,2,4-triazol-5(4H)-one;1-(2,4-dichlorophenyl)-4,5-dihydro-3-methyl-1H-1,2,4-triazol-5-one;2-(2,4-dichlorophenyl)-5-methyl-2,4-dihydro-1,2,4-triazol-3-one;4,5-dihydro-1-(2,4-dichlorophenyl)-3-methyl-5-oxo-1H-1,2,4-triazole;

Chemical Property of 2-(2,4-DICHLORO-PHENYL)-5-METHYL-2,4-DIHYDRO-[1,2,4]TRIAZOL-3-ONE

Chemical Property:

• PSA: 50.68000
• LogP: 2.17580

Purity/Quality:

99% ^*data from raw suppliers

2-(2,4-DICHLORO-PHENYL)-5-METHYL-2,4-DIHYDRO[1,2,4]TRIAZOL-3-ONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(2,4-DICHLORO-PHENYL)-5-METHYL-2,4-DIHYDRO-[1,2,4]TRIAZOL-3-ONE

There total 6 articles about 2-(2,4-DICHLORO-PHENYL)-5-METHYL-2,4-DIHYDRO-[1,2,4]TRIAZOL-3-ONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.7%

2-(2,4-dichlorophenyl)-5-methyl-1,2,4-triazolidin-3-one → 4,5-dihydro-1-(2,4-dichlorophenyl)-3-methyl-1,2,4-triazol-5(1H)-one (79604-49-2)

Guidance literature:

With oxygen; pyrographite; In water; tert-butyl alcohol; at 60 ℃; for 2.5h; under 750.075 Torr; Temperature; Pressure; Reagent/catalyst;

Reference yield: 96.0%

4-acetyl-1-(2,4-dichlorophenyl)-3,3-dimethyl-1,2,4-triazolidin-5-one (133902-78-0) → 4,5-dihydro-1-(2,4-dichlorophenyl)-3-methyl-1,2,4-triazol-5(1H)-one (79604-49-2)

Guidance literature:

With sulfuric acid; acetic acid; at 90 - 100 ℃; for 0.166667h;

Reference yield: 92.0%

2-(2-(2,4-dichlorophenyl)hydrazono)propanoic acid (103998-84-1) → 4,5-dihydro-1-(2,4-dichlorophenyl)-3-methyl-1,2,4-triazol-5(1H)-one (79604-49-2)

Guidance literature:

With diphenyl phosphoryl azide; triethylamine; In toluene; Reflux;

DOI:10.3390/molecules15129024

upstream raw materials:

4-acetyl-1-(2,4-dichlorophenyl)-3,3-dimethyl-1,2,4-triazolidin-5-one

acetone-(2,4-dichloro-phenylhydrazone)

2-(2-(2,4-dichlorophenyl)hydrazono)propanoic acid

2,4-Dichloroaniline

Downstream raw materials:

4,5-dihydro-3-methyl-4-difluoromethyl-1-(2,4-dichlorophenyl)-1,2,4-triazol-5(1H)-one

(E)-methyl 2-(2-((1-(2,4-dichloro-5-(ethylsulfonamido)phenyl)-3-methyl-5-oxo-1H-1,2,4-triazol-4(5H)-yl)methyl)phenyl)-2-(methoxyimino)acetate

(E)-methyl 2-(2-((1-(2,4-dichloro-5-(phenylsulfonamido)phenyl)-3-methyl-5-oxo-1H-1,2,4-triazol-4(5H)-yl)methyl)phenyl)-2-(methoxyimino)acetate

methyl 2-((1-(2,4-dichloro-5-(methylsulfonamido)phenyl)-3-methyl-5-oxo-1H-1,2,4-triazol-4(5H)-yl)methyl)phenyl(methoxy)carbamate