4-(4-Chloroquinazolin-2-yl)-N,N-dimethylaniline

Base Information

Chemical Name:4-(4-Chloroquinazolin-2-yl)-N,N-dimethylaniline
CAS No.:79916-53-3
Molecular Formula:C₁₆H₁₄ClN₃
Molecular Weight:283.76
Hs Code.:
DSSTox Substance ID:DTXSID401221833

Synonyms:4-(4-Chloroquinazolin-2-yl)-N,N-dimethylaniline;79916-53-3;SCHEMBL10753859;ZUWQMICNQFRGOU-UHFFFAOYSA-N;DTXSID401221833;MFCD13464749;BS-50970;CS-0188439;EN300-67831;F51029;4-(4-Chloro-2-quinazolinyl)-N,N-dimethylbenzenamine

Suppliers and Price of 4-(4-Chloroquinazolin-2-yl)-N,N-dimethylaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 4-(4-Chloroquinazolin-2-yl)-N,N-dimethylaniline

Chemical Property:

XLogP3:4.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:283.0876252
Heavy Atom Count:20
Complexity:315

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN(C)C1=CC=C(C=C1)C2=NC3=CC=CC=C3C(=N2)Cl

Technology Process of 4-(4-Chloroquinazolin-2-yl)-N,N-dimethylaniline

There total 5 articles about 4-(4-Chloroquinazolin-2-yl)-N,N-dimethylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 2-[4-(dimethylamino)phenyl]quinazolin-4-ol

: 79916-53-3
4-(4-chloroquinazolin-2-yl)-N,N-dimethylaniline

Guidance literature:: With trichlorophosphate; at 140 ℃; for 5h; Inert atmosphere;

Reference yield:

: 2‐(4‐(dimethylamino)phenyl)quinazolin‐4(3H)‐one

: 79916-53-3
4-(4-chloroquinazolin-2-yl)-N,N-dimethylaniline

Guidance literature:: With N,N-dimethyl-aniline; trichlorophosphate; at 0 ℃; Reflux;
DOI:10.1016/j.ejmech.2016.01.001

Reference yield:

: 28144-70-9,88-68-6
anthranilic acid amide

: 79916-53-3
4-(4-chloroquinazolin-2-yl)-N,N-dimethylaniline

Guidance literature:: Multi-step reaction with 2 steps

1: sodium sulfite / N,N-dimethyl acetamide / 150 °C / Inert atmosphere

2: trichlorophosphate / 5 h / 140 °C / Inert atmosphere

With sodium sulfite; trichlorophosphate; In N,N-dimethyl acetamide;