6-Heptyn-3-one, 1-[(2R,3R,5R)-5-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]tetrahydro- 3-[(triethylsilyl)oxy]-2-furanyl]-2-methyl-7-(trimethylsilyl)-, (2R)-

Base Information

Chemical Name:6-Heptyn-3-one, 1-[(2R,3R,5R)-5-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]tetrahydro- 3-[(triethylsilyl)oxy]-2-furanyl]-2-methyl-7-(trimethylsilyl)-, (2R)-
CAS No.:799296-84-7
Molecular Formula:C38H60O4Si3
Molecular Weight:665.148
Hs Code.:

6-Heptyn-3-one,
1-[(2R,3R,5R)-5-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]tetrahydro-
3-[(triethylsilyl)oxy]-2-furanyl]-2-methyl-7-(trimethylsilyl)-, (2R)-

Synonyms:

Suppliers and Price of 6-Heptyn-3-one, 1-[(2R,3R,5R)-5-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]tetrahydro- 3-[(triethylsilyl)oxy]-2-furanyl]-2-methyl-7-(trimethylsilyl)-, (2R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6-Heptyn-3-one, 1-[(2R,3R,5R)-5-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]tetrahydro- 3-[(triethylsilyl)oxy]-2-furanyl]-2-methyl-7-(trimethylsilyl)-, (2R)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6-Heptyn-3-one, 1-[(2R,3R,5R)-5-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]tetrahydro- 3-[(triethylsilyl)oxy]-2-furanyl]-2-methyl-7-(trimethylsilyl)-, (2R)-

There total 8 articles about 6-Heptyn-3-one, 1-[(2R,3R,5R)-5-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]tetrahydro- 3-[(triethylsilyl)oxy]-2-furanyl]-2-methyl-7-(trimethylsilyl)-, (2R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 799296-76-7
(R)-1-[(2R,3R,5R)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-3-triethylsilanyloxy-tetrahydro-furan-2-yl]-2-methyl-7-trimethylsilanyl-hept-6-yn-3-ol

: 799296-84-7
(R)-1-[(2R,3R,5R)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-3-triethylsilanyloxy-tetrahydro-furan-2-yl]-2-methyl-7-trimethylsilanyl-hept-6-yn-3-one

Guidance literature:: With N-methyl-2-indolinone; tetrapropylammonium perruthennate; 4 A molecular sieve; In dichloromethane; at 20 ℃;
DOI:10.1021/ol048581a

Reference yield:

: 58479-61-1
tert-butylchlorodiphenylsilane

: 799296-84-7
(R)-1-[(2R,3R,5R)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-3-triethylsilanyloxy-tetrahydro-furan-2-yl]-2-methyl-7-trimethylsilanyl-hept-6-yn-3-one

Guidance literature:: Multi-step reaction with 6 steps

1.1: 70 percent / imidazole / CH₂Cl₂ / 12 h / 20 °C

2.1: 86 percent / H₂ / Pd(OH)2/C / ethyl acetate / 12 h / 20 °C / 760 Torr

3.1: 83 percent / imidazole; DMAP / CH₂Cl₂ / 24 h / 20 °C

4.1: 73 percent / DMSO; (COCl)2 / CH₂Cl₂ / -78 - -35 °C

5.1: t-BuLi / diethyl ether; hexane / 0.75 h / -78 - 20 °C

5.2: CuI / diethyl ether; hexane / 0.08 h / -78 °C

5.3: 65 percent / diethyl ether; hexane / 1 h / -78 °C

6.1: 4 Angstroem molecular sieves; NMO; TPAP / CH₂Cl₂ / 20 °C

With 1H-imidazole; dmap; N-methyl-2-indolinone; tetrapropylammonium perruthennate; oxalyl dichloride; 4 A molecular sieve; hydrogen; tert.-butyl lithium; dimethyl sulfoxide; palladium dihydroxide; In diethyl ether; hexane; dichloromethane; ethyl acetate; 4.1: Swern oxidation;
DOI:10.1021/ol048581a

Reference yield:

: (2R,3R,5R)-2-((R)-3-Benzyloxy-2-methyl-propyl)-5-hydroxymethyl-tetrahydro-furan-3-ol

: 799296-84-7
(R)-1-[(2R,3R,5R)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-3-triethylsilanyloxy-tetrahydro-furan-2-yl]-2-methyl-7-trimethylsilanyl-hept-6-yn-3-one

Guidance literature:: Multi-step reaction with 6 steps

1.1: 70 percent / imidazole / CH₂Cl₂ / 12 h / 20 °C

2.1: 86 percent / H₂ / Pd(OH)2/C / ethyl acetate / 12 h / 20 °C / 760 Torr

3.1: 83 percent / imidazole; DMAP / CH₂Cl₂ / 24 h / 20 °C

4.1: 73 percent / DMSO; (COCl)2 / CH₂Cl₂ / -78 - -35 °C

5.1: t-BuLi / diethyl ether; hexane / 0.75 h / -78 - 20 °C

5.2: CuI / diethyl ether; hexane / 0.08 h / -78 °C

5.3: 65 percent / diethyl ether; hexane / 1 h / -78 °C

6.1: 4 Angstroem molecular sieves; NMO; TPAP / CH₂Cl₂ / 20 °C

With 1H-imidazole; dmap; N-methyl-2-indolinone; tetrapropylammonium perruthennate; oxalyl dichloride; 4 A molecular sieve; hydrogen; tert.-butyl lithium; dimethyl sulfoxide; palladium dihydroxide; In diethyl ether; hexane; dichloromethane; ethyl acetate; 4.1: Swern oxidation;
DOI:10.1021/ol048581a