Chlorhexidine

Base Information

Chemical Name:Chlorhexidine
CAS No.:3697-42-5
Deprecated CAS:111883-36-4,328933-19-3,1520991-69-8,328933-19-3
Molecular Formula:C22H30Cl2N10^.2ClH
Molecular Weight:578.375
Hs Code.:29252900
European Community (EC) Number:200-238-7,223-026-6
UNII:R4KO0DY52L
DSSTox Substance ID:DTXSID2033314
Wikipedia:Chlorhexidine
NCI Thesaurus Code:C364
RXCUI:2358
Pharos Ligand ID:8Q7TDW6124W6
Metabolomics Workbench ID:43153
ChEMBL ID:CHEMBL790
Mol file:3697-42-5.mol

Synonyms:Acetate, Chlorhexidine;Chlorhexidine;Chlorhexidine Acetate;Chlorhexidine Hydrochloride;Hydrochloride, Chlorhexidine;MK 412A;MK-412A;MK412A;Novalsan;Sebidin A;Tubulicid

Suppliers and Price of Chlorhexidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Chlorhexidine Dihydrochloride
100g
$ 215.00

TRC
Chlorhexidine Dihydrochloride
25g
$ 155.00

TCI Chemical
Chlorhexidine Dihydrochloride >96.0%(T)
25g
$ 122.00

TCI Chemical
Chlorhexidine Dihydrochloride >96.0%(T)
5g
$ 51.00

Sigma-Aldrich
Chlorhexidine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
500mg
$ 75.50

Sigma-Aldrich
Chlorhexidine dihydrochloride ≥98%
5g
$ 55.00

Sigma-Aldrich
Chlorhexidine dihydrochloride European Pharmacopoeia (EP) Reference Standard
$ 190.00

Sigma-Aldrich
Chlorhexidine dihydrochloride European Pharmacopoeia (EP) Reference Standard
c1540000
$ 190.00

Sigma-Aldrich
Chlorhexidine dihydrochloride ≥98%
25g
$ 183.00

DC Chemicals
ChlorhexidineHCl >99%
1 g
$ 1000.00

Total 179 raw suppliers

Chemical Property of Chlorhexidine

Chemical Property:

Appearance/Colour:white crystalline solid
Vapor Pressure:2.11E-19mmHg at 25°C
Melting Point:111-116 °C
Boiling Point:699.3 °C at 760 mmHg
Flash Point:376.7 °C
PSA：167.58000
Density:1.284[at 20℃]
LogP:7.88780
Storage Temp.:2-8°C
Solubility.:Sparingly soluble in water and in propylene glycol, very slightly soluble in ethanol (96 per cent).
Water Solubility.:0.06 g/100 mL (20 ºC)
XLogP3:0.1
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:13
Exact Mass:504.2031964
Heavy Atom Count:34
Complexity:649

Purity/Quality:

98.0-102.0% ^*data from raw suppliers

Chlorhexidine Dihydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn,Xi
Hazard Codes:Xn,Xi
Statements: 22-36/37/38
Safety Statements: 53-45-61-36-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Chemical Classes:Other Uses -> Biocides/Disinfectants
Canonical SMILES:C1=CC(=CC=C1NC(=NC(=NCCCCCCN=C(N)N=C(N)NC2=CC=C(C=C2)Cl)N)N)Cl
Isomeric SMILES:C1=CC(=CC=C1N/C(=N/C(=NCCCCCCN=C(/N=C(/NC2=CC=C(C=C2)Cl)\N)N)N)/N)Cl
Recent ClinicalTrials:Decolonization to Reduce After-Surgery Events of Surgical Site Infection
Recent EU Clinical Trials:Prospective Randomized Evaluation of Emerging Novel Treatments for Infection prophylaxis in Total Joint Replacement (PREVENT-iT): A Pilot Study
Recent NIPH Clinical Trials:Efficacy of oranexidine gluconate in the prevention of catheter-related bloodstream infections
Uses antibacterial (topical), disinfectant chlorhexidine dihydrochloride is a preservative, it functions primarily as an anti-microbial, helping control the proliferation of bacteria, fungi, or yeast in a product. It is a bisbiguanide with bacteriostatic activity. Antiseptic; disinfectant

Technology Process of Chlorhexidine

There total 1 articles about Chlorhexidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.3%