3-Hydroxy-1,2,3,4-tetrahydrobenzo[h]quinoline

Base Information

Chemical Name:3-Hydroxy-1,2,3,4-tetrahydrobenzo[h]quinoline
CAS No.:5423-67-6
Molecular Formula:C13H13NO
Molecular Weight:199.252
Hs Code.:29334900
European Community (EC) Number:226-556-6
NSC Number:13233
DSSTox Substance ID:DTXSID401252939
Nikkaji Number:J218.004I
ChEMBL ID:CHEMBL1868082
Mol file:5423-67-6.mol

Synonyms:1,2,3,4-Tetrahydrobenzo[h]quinolin-3-ol;3-Hydroxy-1,2,3,4-tetrahydrobenzo[h]quinoline;NSC 13233;

Suppliers and Price of 3-Hydroxy-1,2,3,4-tetrahydrobenzo[h]quinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Frontier Specialty Chemicals
1,2,3,4-Tetrahydrobenzo[h]quinolin-3-ol 97%
1g
$ 196.00

Frontier Specialty Chemicals
1,2,3,4-Tetrahydrobenzo[h]quinolin-3-ol 97%
250mg
$ 99.00

Frontier Specialty Chemicals
1,2,3,4-Tetrahydrobenzo[h]quinolin-3-ol 97%
5g
$ 570.00

Crysdot
1,2,3,4-Tetrahydrobenzo[h]quinolin-3-ol 95+%
10g
$ 718.00

Crysdot
1,2,3,4-Tetrahydrobenzo[h]quinolin-3-ol 95+%
5g
$ 429.00

American Custom Chemicals Corporation
1,2,3,4-TETRAHYDRO-BENZO[H]QUINOLIN-3-OL 95.00%
1G
$ 736.12

American Custom Chemicals Corporation
1,2,3,4-TETRAHYDRO-BENZO[H]QUINOLIN-3-OL 95.00%
5G
$ 1210.63

American Custom Chemicals Corporation
1,2,3,4-TETRAHYDRO-BENZO[H]QUINOLIN-3-OL 95.00%
2.5G
$ 1011.60

Alichem
1,2,3,4-Tetrahydrobenzo[h]quinolin-3-ol
1g
$ 150.80

Alichem
1,2,3,4-Tetrahydrobenzo[h]quinolin-3-ol
5g
$ 467.64

Total 54 raw suppliers

Chemical Property of 3-Hydroxy-1,2,3,4-tetrahydrobenzo[h]quinoline

Chemical Property:

Vapor Pressure:5.87E-08mmHg at 25°C
Melting Point:148-150 °C
Refractive Index:1.672
Boiling Point:424.3°C at 760mmHg
PKA:14.33±0.20(Predicted)
Flash Point:210.5°C
PSA：32.26000
Density:1.219g/cm³
LogP:2.30670
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:199.099714038
Heavy Atom Count:15
Complexity:231

Purity/Quality:

98%, ^*data from raw suppliers

1,2,3,4-Tetrahydrobenzo[h]quinolin-3-ol 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(CNC2=C1C=CC3=CC=CC=C32)O

Technology Process of 3-Hydroxy-1,2,3,4-tetrahydrobenzo[h]quinoline

There total 5 articles about 3-Hydroxy-1,2,3,4-tetrahydrobenzo[h]quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 134-32-7
1-amino-naphthalene

: 106-89-8,24969-06-0,13403-37-7
epichlorohydrin

: 5423-67-6
3-hydroxy-7,8-benzo-1,2,3,4-tetrahydroquinoline

Guidance literature:: In 1,2-dichloro-benzene; at 160 ℃; for 7h;
DOI:10.1007/s11172-006-0378-9

Reference yield:

: C₂₅H₁₉B₂NO₄

: 5423-67-6
3-hydroxy-7,8-benzo-1,2,3,4-tetrahydroquinoline

Guidance literature:: With sodium perborate tetrahydrate; In tetrahydrofuran; water; at 50 ℃; for 1h; Inert atmosphere;
DOI:10.1002/adsc.201901050

Reference yield:

: 230-27-3
7,8-benzoquinoline

: 5423-67-6
3-hydroxy-7,8-benzo-1,2,3,4-tetrahydroquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: tris(pentafluorophenyl)borate / chloroform / 15 h / 85 °C / Inert atmosphere

2: sodium perborate tetrahydrate / water; tetrahydrofuran / 1 h / 50 °C / Inert atmosphere

With sodium perborate tetrahydrate; tris(pentafluorophenyl)borate; In tetrahydrofuran; chloroform; water;
DOI:10.1002/adsc.201901050