2-(Hydroxymethyl)-6-[[3,4,5-trihydroxy-6-(oxiran-2-ylmethoxy)oxan-2-yl]methoxy]oxane-3,4,5-triol

Base Information

Chemical Name:2-(Hydroxymethyl)-6-[[3,4,5-trihydroxy-6-(oxiran-2-ylmethoxy)oxan-2-yl]methoxy]oxane-3,4,5-triol
CAS No.:101628-44-8
Molecular Formula:C₁₅H₂₆O₁₂
Molecular Weight:398.364
Hs Code.:
DSSTox Substance ID:DTXSID10906408
Mol file:101628-44-8.mol

Synonyms:2,3-EPGG;2,3-epoxypropyl O-galactopyranosyl(1-6)galactopyranoside;2,3-epoxypropyl O-galactopyranosyl(1-6)galactopyranoside, S-isomer

Suppliers and Price of 2-(Hydroxymethyl)-6-[[3,4,5-trihydroxy-6-(oxiran-2-ylmethoxy)oxan-2-yl]methoxy]oxane-3,4,5-triol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(Hydroxymethyl)-6-[[3,4,5-trihydroxy-6-(oxiran-2-ylmethoxy)oxan-2-yl]methoxy]oxane-3,4,5-triol

Chemical Property:

Vapor Pressure:1.26E-23mmHg at 25°C
Boiling Point:715.2°Cat760mmHg
Flash Point:386.3°C
PSA：191.06000
Density:1.66g/cm³
LogP:-4.97410
XLogP3:-4.5
Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:7
Exact Mass:398.14242626
Heavy Atom Count:27
Complexity:480

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(O1)COC2C(C(C(C(O2)COC3C(C(C(C(O3)CO)O)O)O)O)O)O

Technology Process of 2-(Hydroxymethyl)-6-[[3,4,5-trihydroxy-6-(oxiran-2-ylmethoxy)oxan-2-yl]methoxy]oxane-3,4,5-triol

There total 9 articles about 2-(Hydroxymethyl)-6-[[3,4,5-trihydroxy-6-(oxiran-2-ylmethoxy)oxan-2-yl]methoxy]oxane-3,4,5-triol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 101528-74-9,101628-43-7
2,3-epoxypropyl O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1-6)-2,3,4-tri-O-acetyl-β-D-galactopyranoside

: 101528-75-0,101628-44-8
2,3-epoxypropyl O-β-D-galactopyranosyl-(1-6)-β-D-galactopyranoside

Guidance literature:: With sodium methylate; In methanol; for 0.5h; Ambient temperature;
DOI:10.1016/S0008-6215(00)90441-5

Reference yield:

: 78096-85-2
2,3,4-tri-O-acetyl-6-O-(chloroacetyl)-α-D-galactopyranosyl bromide

: 101528-75-0,101628-44-8
2,3-epoxypropyl O-β-D-galactopyranosyl-(1-6)-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 5 steps

1: Hg(CN)2, HgBr₂, Drierite / toluene / 18 h / Ambient temperature

2: 1) thiourea 2) sym-collidine / 1) CH₂Cl₂, RT, overnight, 2) CH₂Cl₂, reflux, 4 h

3: 78 percent / Hg(CN)2, HgBr₂, Drierite / benzene / Ambient temperature

4: 84 percent / m-chloroperbenzoic acid / CH₂Cl₂ / 8 h / Heating

5: 62 percent / 1M NaOMe / methanol / 0.5 h / Ambient temperature

With 2,4,6-trimethyl-pyridine; calcium sulfate; sodium methylate; mercury(II) cyanide; thiourea; 3-chloro-benzenecarboperoxoic acid; mercury dibromide; In methanol; dichloromethane; toluene; benzene;
DOI:10.1016/S0008-6215(00)90441-5

Reference yield:

: 101528-69-2
allyl 2,3,4-tri-O-acetyl-6-O-chloroacetyl-β-D-galactopyranoside

: 101528-75-0,101628-44-8
2,3-epoxypropyl O-β-D-galactopyranosyl-(1-6)-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 4 steps

1: 1) thiourea 2) sym-collidine / 1) CH₂Cl₂, RT, overnight, 2) CH₂Cl₂, reflux, 4 h

2: 78 percent / Hg(CN)2, HgBr₂, Drierite / benzene / Ambient temperature

3: 84 percent / m-chloroperbenzoic acid / CH₂Cl₂ / 8 h / Heating

4: 62 percent / 1M NaOMe / methanol / 0.5 h / Ambient temperature

With 2,4,6-trimethyl-pyridine; calcium sulfate; sodium methylate; mercury(II) cyanide; thiourea; 3-chloro-benzenecarboperoxoic acid; mercury dibromide; In methanol; dichloromethane; benzene;
DOI:10.1016/S0008-6215(00)90441-5