Indolidan

Base Information

Chemical Name:Indolidan
CAS No.:100643-96-7
Molecular Formula:C₁₄H₁₅N₃O₂
Molecular Weight:257.292
Hs Code.:
UNII:0751ZOW7OR
DSSTox Substance ID:DTXSID0020739
Nikkaji Number:J326.574I
Wikidata:Q27236256
NCI Thesaurus Code:C175087
ChEMBL ID:CHEMBL38224
Mol file:100643-96-7.mol

Synonyms:1,3-dihydro-3,3-dimethyl-5-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)-2H-indol-2-one;indolidan;LY 195115;LY-195115

Suppliers and Price of Indolidan

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
INDOLIDAN 95.00%
5MG
$ 495.57

Total 7 raw suppliers

Chemical Property of Indolidan

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：77.54000
Density:1.39g/cm³
LogP:1.32700
XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:257.116426730
Heavy Atom Count:19
Complexity:456

Purity/Quality:

99% ^*data from raw suppliers

INDOLIDAN 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C2=C(C=CC(=C2)C3=NNC(=O)CC3)NC1=O)C
Uses Cardiotonic.

Technology Process of Indolidan

There total 4 articles about Indolidan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 100643-97-8
2,3-dihydro-3,3-dimethyl-γ,2-dioxo-1H-indole-5-butanoic acid

: 100643-96-7
indolidan

Guidance literature:: With hydrazine hydrate; In ethanol; for 4h; Heating;
DOI:10.1021/jm00160a006

Reference yield:

: 19155-24-9
3,3-dimethyloxindole

: 100643-96-7
indolidan

Guidance literature:: Multi-step reaction with 2 steps

1: 74 percent / AlCl₃, DMF / 2.5 h / 70 °C

2: 88 percent / hydrazine hydrate / ethanol / 4 h / Heating

With aluminium trichloride; hydrazine hydrate; N,N-dimethyl-formamide; In ethanol;
DOI:10.1021/jm00160a006

Reference yield:

: 72934-84-0
1-acetyl-3,3-dimethylindolin-2-one

: 100643-96-7
indolidan

Guidance literature:: Multi-step reaction with 3 steps

1: 6N aq. HCl / 1.5 h / Heating

2: 74 percent / AlCl₃, DMF / 2.5 h / 70 °C

3: 88 percent / hydrazine hydrate / ethanol / 4 h / Heating

With hydrogenchloride; aluminium trichloride; hydrazine hydrate; N,N-dimethyl-formamide; In ethanol;
DOI:10.1021/jm00160a006