Piroxantrone

Base Information

Chemical Name:Piroxantrone
CAS No.:91441-23-5
Molecular Formula:C₂₁H₂₅N₅O₄
Molecular Weight:411.461
Hs Code.:
Mol file:91441-23-5.mol

Synonyms:Anthra[1,9-cd]pyrazol-6(2H)-one,5-[(3-aminopropyl)amino]-7,10-dihydroxy-2-[2-[(2-hydroxyethyl)amino]ethyl]-(9CI); Dup 942; NCS 349174; Oxantrazole; PD 111815; Piroxantrone

Suppliers and Price of Piroxantrone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Piroxantrone

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:785°Cat760mmHg
Flash Point:428.6°C
PSA：145.66000
Density:1.435g/cm³
LogP:2.05870

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Antineoplastic.

Technology Process of Piroxantrone

There total 8 articles about Piroxantrone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 104740-29-6
5-<(3-aminopropyl)amino>-2-<2-<(2-hydroxyethyl)amino>ethyl>-7,10-bis-(phenylmethoxy)anthra<1,9-cd>pyrazol-6(2H)-one

: 91441-23-5
Piroxantrone

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; acetic acid; for 21h; under 258.6 Torr; Yield given; Parr shaker;
DOI:10.1002/jhet.5570260117

Reference yield:

: 91441-59-7
5-chloro-2-[2-[(2-hydroxyethyl)amino]ethyl]-7,10-bis(phenylmethoxy)anthra[1,9-cd]-pyrazol-6(2H)-one

: 91441-23-5
Piroxantrone

Guidance literature:: Multi-step reaction with 2 steps

1: 67 percent / 3 h / 132 °C

2: H₂ / 20percent Pd(OH)2/C / acetic acid / 4 h / 25 °C / 760 Torr

With hydrogen; palladium dihydroxide; In acetic acid;
DOI:10.1021/jm00384a021

Reference yield:

: 105158-35-8
5-<(3-aminopropyl)amino>-2-<2-<(2-hydroxyethyl)(phenylmethyl)amino>ethyl>-7,10-bis(phenylmethoxy)anthra<1,9-cd>pyrazol-6(2H)-one

: 91441-23-5
Piroxantrone

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; acetic acid; for 5h; under 2585.7 Torr; Yield given; Parr shaker;
DOI:10.1002/jhet.5570260117