AMD 3465 (*Hexahydrobromide*)

Base Information

• Chemical Name: AMD 3465 (*Hexahydrobromide*)
• CAS No.: 185991-07-5
• Molecular Formula: C24H38N6
• Molecular Weight: 410.5987
• Mol file: 185991-07-5.mol

Synonyms:AMD3465 hexahydrobromide;

Chemical Property of AMD 3465 (*Hexahydrobromide*)

Chemical Property:

• Vapor Pressure: 5.1E-13mmHg at 25°C
• Melting Point: >200°C (dec.)
• Boiling Point: 570.3°Cat760mmHg
• Flash Point: 298.7°C
• PSA: 64.25000
• Density: 1.022g/cm³
• LogP: 8.79980
• Storage Temp.: -20°C
• Solubility.: DMSO (Slightly), Methanol (Very Slightly), Water (Slightly)

Purity/Quality:

99%, ^*data from raw suppliers

AMD 3465 hexahydrobromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: AMD 3465 is a CXCR4 antagonist and in combination with monoclonal antibody, was shown to be potentially effective in reducing tumor growth and increasing survival in patient with B cell lymphoma

Technology Process of AMD 3465 (*Hexahydrobromide*)

There total 1 articles about AMD 3465 (*Hexahydrobromide*) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C36H65N6O9P3 → AMD 3465 (185991-07-5)

Guidance literature:

With hydrogen bromide; In acetic acid; at 20 ℃; for 14h;

DOI:10.1021/jm901530b

Reference yield:

sodium [99Tc]pertechnetate (13718-28-0,65146-78-3,131626-77-2,34316-43-3) + AMD 3465 (185991-07-5) → C24H38N6O2Tc

Guidance literature:

With hydrogenchloride; tin(II) chloride dihdyrate; Rochelle's salt; In aq. phosphate buffer; at 100 ℃; for 0.333333h; pH=10 - 11; pH-value; Temperature;

DOI:10.1002/jlcr.3608

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