Quinoline, 3-(2-phenylethyl)-

Base Information

• Chemical Name: Quinoline, 3-(2-phenylethyl)-
• CAS No.: 80998-89-6
• Molecular Formula: C17H15N
• Molecular Weight: 233.313
• Mol file: 80998-89-6.mol

Synonyms:

Chemical Property of Quinoline, 3-(2-phenylethyl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Quinoline, 3-(2-phenylethyl)-

There total 8 articles about Quinoline, 3-(2-phenylethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

3-bromoquinoline (5332-24-1) + 2,4,6-triphenyl-1-(2-phenylethyl)pyridinium tetrafluoroborate → 3-phenethylquinoline (80998-89-6)

Guidance literature:

With manganese; (1,2-dimethoxyethane)dichloronickel(II); 4,4'-Dimethoxy-2,2'-bipyridin; magnesium chloride; In 1-methyl-pyrrolidin-2-one; at 80 ℃; for 24h; Schlenk technique; Sealed tube; Inert atmosphere;

DOI:10.1021/acs.orglett.9b01014

Reference yield: 78.0%

triethylsilane (617-86-7) + 3-(2-phenylethynyl)quinoline (70437-03-5) → 3-phenethylquinoline (80998-89-6)

Guidance literature:

With water; at 90 ℃; for 16h; Inert atmosphere; Sealed tube;

DOI:10.1002/adsc.201300641

Reference yield: 75.0%

C17H19N → 3-phenethylquinoline (80998-89-6)

Guidance literature:

With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; tetrabutylammonium tetrafluoroborate; In water; acetonitrile; at 20 ℃; for 4h; Electrochemical reaction;

DOI:10.1021/acscatal.7b04137

upstream raw materials:

3-(2-phenylethynyl)quinoline

phenylacetylene

triethylsilane

styrene

Refernces

• 1、 Liao, Jennie,Basch, Corey H.,Hoerrner, Megan E.,Talley, Michael R.,Boscoe, Brian P.,Tucker, Joseph W.,Garnsey, Michelle R.,Watson, Mary P.. "Deaminative Reductive Cross-Electrophile Couplings of Alkylpyridinium Salts and Aryl Bromides". . p. 2941 - 2946. Retrieved 2019/04/30.
• 2、 Planellas, Marc,Guo, Wusheng,Alonso, Francisco,Yus, Miguel,Shafir, Alexandr,Pleixats, Roser,Parella, Teodor. "Hydrosilylation of internal alkynes catalyzed by tris- Imidazolium salt-Stabilized palladium nanoparticles". . p. 179 - 188. Retrieved 2014/03/21.