Dazoxiben hydrochloride

Base Information

Chemical Name:Dazoxiben hydrochloride
CAS No.:74226-22-5
Molecular Formula:C12H13ClN2O3
Molecular Weight:268.6962
Hs Code.:
UNII:G5AI939LWF
DSSTox Substance ID:DTXSID40225215
Wikidata:Q27278786
NCI Thesaurus Code:C169879
Pharos Ligand ID:BU5T7G9Q3BUM
ChEMBL ID:CHEMBL537708

Synonyms:4-(2-(1H-imidazol-1-yl)ethoxy)benzoic acid hydrochloride;dazoxiben;dazoxiben hydrochloride;UK 37248;UK 37248-01;UK-37,248;UK-37,248-01;UK-37248

Suppliers and Price of Dazoxiben hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 9 raw suppliers

Chemical Property of Dazoxiben hydrochloride

Chemical Property:

Vapor Pressure:1.83E-10mmHg at 25°C
Boiling Point:491.2°Cat760mmHg
Flash Point:250.9°C
Density:g/cm³
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:268.0614700
Heavy Atom Count:18
Complexity:252

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(=O)O)OCCN2C=CN=C2.Cl

Technology Process of Dazoxiben hydrochloride

There total 6 articles about Dazoxiben hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 75912-57-1
4-<2-(1H-imidazol-1-yl)ethoxy>benzamide

: 74226-22-5
4-[2-(1-imidazolyl)ethoxy]benzoic acid hydrochloride

Guidance literature:: With sodium hydroxide; for 2h; Heating;
DOI:10.1021/jm00148a009

Reference yield: 79.0%

: 85938-29-0
1-acetyl-3-[2-(4-ethoxycarbonylphenoxy)ethyl]-imidazolium iodide

: 74226-22-5
4-[2-(1-imidazolyl)ethoxy]benzoic acid hydrochloride

Guidance literature:: In 2N-hydrochloric acid;

Reference yield:

: 36616-30-5
2-(4-carbamoylphenoxy)-ethyl chloride

: 74226-22-5
4-[2-(1-imidazolyl)ethoxy]benzoic acid hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH / 1.) DMF, 100 deg C, 10 min, 2.) DMF, heating, 5.5 h

2: 87 percent / 5N aq. NaOH / 2 h / Heating

With sodium hydroxide; sodium hydride;
DOI:10.1021/jm00148a009