5-Chloro-2',3'-O-isopropylidene-D-uridine

Base Information

Chemical Name:5-Chloro-2',3'-O-isopropylidene-D-uridine
CAS No.:81356-82-3
Molecular Formula:C₁₂H₁₅ClN₂O₆
Molecular Weight:318.714
Hs Code.:
Mol file:81356-82-3.mol

Synonyms:5-Chloro-2',3'-O-(1-methylethylidene)uridine;2',3'-O-Isopropylidene-5-chlorouridine;

Suppliers and Price of 5-Chloro-2',3'-O-isopropylidene-D-uridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2’,3’-O-Isopropylidene-5-chlorouridine
100mg
$ 85.00

TRC
2’,3’-O-Isopropylidene-5-chlorouridine
50mg
$ 55.00

Biosynth Carbosynth
5-Chloro-2',3'-O-isopropylideneuridine
250 mg
$ 262.50

Biosynth Carbosynth
5-Chloro-2',3'-O-isopropylideneuridine
100 mg
$ 158.00

Biosynth Carbosynth
5-Chloro-2',3'-O-isopropylideneuridine
50 mg
$ 89.50

American Custom Chemicals Corporation
2',3'-O-ISOPROPYLIDENE-5-CHLOROURIDINE 95.00%
5MG
$ 503.67

Total 5 raw suppliers

Chemical Property of 5-Chloro-2',3'-O-isopropylidene-D-uridine

Chemical Property:

PSA：102.78000
LogP:-0.40020

Purity/Quality:

97% ^*data from raw suppliers

2’,3’-O-Isopropylidene-5-chlorouridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 2’,3’-O-Isopropylidene-5-chlorouridine (cas# 81356-82-3) is a compound useful in organic synthesis.

Technology Process of 5-Chloro-2',3'-O-isopropylidene-D-uridine

There total 5 articles about 5-Chloro-2',3'-O-isopropylidene-D-uridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 362-43-6
2',3'-O-isopropylideneuridine

: 81356-82-3
2',3'-O-isopropylidene-5-chlorouridine

Guidance literature:: With sodium hydrogencarbonate; lithium chloride; In acetonitrile; Ambient temperature; electrolysis (Pt electrodes, SCE reference, LiClO₄ as supporting electrolyte);
DOI:10.1016/0040-4039(93)88044-J

Reference yield:

: 3370-68-1,3266-87-3
2',3',5'-tri-O-acetyl-5-chlorouridine

: 81356-82-3
2',3'-O-isopropylidene-5-chlorouridine

Guidance literature:: Multi-step reaction with 2 steps

1: ammonia / methanol / 5 h

2: sulfuric acid / 7 h

With sulfuric acid; ammonia; In methanol;
DOI:10.1039/c2cc31597a

Reference yield:

: 58-96-8
uridine

: 81356-82-3
2',3'-O-isopropylidene-5-chlorouridine

Guidance literature:: Multi-step reaction with 4 steps

1: pyridine; dmap / 4 h / 25 °C

2: ammonium cerium (IV) nitrate; lithium chloride / acetic acid; acetonitrile / 8 h / 80 °C

3: ammonia / methanol / 5 h

4: sulfuric acid / 7 h

With pyridine; dmap; ammonium cerium (IV) nitrate; sulfuric acid; ammonia; lithium chloride; In methanol; acetic acid; acetonitrile;
DOI:10.1039/c2cc31597a