[4-(4-Pentylcyclohexyl)phenyl]methanol

Base Information

• Chemical Name: [4-(4-Pentylcyclohexyl)phenyl]methanol
• CAS No.: 82380-25-4
• Molecular Formula: C18H28O
• Molecular Weight: 260.42
• DSSTox Substance ID: DTXSID40408647
• Mol file: 82380-25-4.mol

Synonyms:[4-(4-pentylcyclohexyl)phenyl]methanol;82380-25-4;4-(trans-4-pentylcyclohexyl)benzyl alcohol;SCHEMBL2969419;SCHEMBL2969423;SCHEMBL15725344;DTXSID40408647;DZUHFSSAWKOKHE-JCNLHEQBSA-N;AKOS001482992;EU-0033432;SR-01000388870;SR-01000388870-1

Chemical Property of [4-(4-Pentylcyclohexyl)phenyl]methanol

Chemical Property:

• XLogP3: 6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 6
• Exact Mass: 260.214015512
• Heavy Atom Count: 19
• Complexity: 222

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCC1CCC(CC1)C2=CC=C(C=C2)CO

Technology Process of [4-(4-Pentylcyclohexyl)phenyl]methanol

There total 2 articles about [4-(4-Pentylcyclohexyl)phenyl]methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-(Trans-4'-pentylcyclohexyl)-benzoic acid (65355-30-8) → 4-(trans-4-pentylcyclohexyl)benzyl alcohol (82380-25-4)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; Heating;

DOI:10.1002/hlca.19850680535

Reference yield:

4-(trans-4-pentylcyclohexyl)benzonitrile (61204-01-1,62788-05-0) → 4-(trans-4-pentylcyclohexyl)benzyl alcohol (82380-25-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid, water / 5 h / Heating

2: lithium aluminum hydride / tetrahydrofuran / Ambient temperature

With lithium aluminium tetrahydride; sulfuric acid; water; In tetrahydrofuran;

Reference yield: 64.0%

4-(trans-4-pentylcyclohexyl)benzyl alcohol (82380-25-4) → 4-(trans-4-pentylcyclohexyl)benzyl bromide (82380-26-5)

Guidance literature:

With bromine; triphenylphosphine; 1.) MeCN, 0-10 deg C, rt, 1 h; 2.) MeCN, rt, 30 min; 3.) 120 deg C, 15 min;

DOI:10.1002/hlca.19850680535

upstream raw materials:

4-(Trans-4'-pentylcyclohexyl)-benzoic acid

4-(trans-4-pentylcyclohexyl)benzonitrile

Downstream raw materials:

4-(trans-4-pentylcyclohexyl)benzaldehyde

4-(trans-4-pentylcyclohexyl)benzyl bromide

1-(4-chloro-2-fluorophenyl)-2-<4-(trans-4-pentylcyclohexyl)phenyl>ethane

2-[4-(4-Pentyl-cyclohexyl)-phenyl]-ethanol