Phenol, 3-[(1Z)-1-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]-

Base Information

Chemical Name:Phenol, 3-[(1Z)-1-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]-
CAS No.:82413-24-9
Molecular Formula:C₂₆H₂₉NO₂
Molecular Weight:387.522
Hs Code.:
DSSTox Substance ID:DTXSID801137709
ChEMBL ID:CHEMBL486

Synonyms:CHEMBL486;JPBUGVXOVXSGAV-QPLCGJKRSA-N;DTXSID801137709;Phenol, 3-[(1Z)-1-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]-;82413-24-9

Suppliers and Price of Phenol, 3-[(1Z)-1-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Phenol, 3-[(1Z)-1-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]-

Chemical Property:

XLogP3:6.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:387.219829168
Heavy Atom Count:29
Complexity:501

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCCN(C)C)C3=CC(=CC=C3)O
Isomeric SMILES:CC/C(=C(\C1=CC=CC=C1)/C2=CC=C(C=C2)OCCN(C)C)/C3=CC(=CC=C3)O

Technology Process of Phenol, 3-[(1Z)-1-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]-

There total 5 articles about Phenol, 3-[(1Z)-1-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 106-41-2
4-bromo-phenol

: 82413-24-9
3-{1-[1-[4-(2-Dimethylamino-ethoxy)-phenyl]-1-phenyl-meth-(Z)-ylidene]-propyl}-phenol

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / NaH, DMF / 3 h / 85 - 90 °C

2: 1.) C₂H₅MgBr, 3.) HCl

With hydrogenchloride; ethylmagnesium bromide; sodium hydride; N,N-dimethyl-formamide;
DOI:10.1021/jm00351a010

Reference yield:

: 29955-26-8
1′-(3-methoxyphenyl)-2′-phenylethan-2′-one

: 82413-24-9
3-{1-[1-[4-(2-Dimethylamino-ethoxy)-phenyl]-1-phenyl-meth-(Z)-ylidene]-propyl}-phenol

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) NaH / 1.) DMF, 2.) DMF

2: 79 percent / 48percent aq. HBr, acetic acid / 4 h / Heating

3: 98percent H₂SO₄ / 12 h / Ambient temperature

4: 1.) C₂H₅MgBr, 3.) HCl

With hydrogenchloride; sulfuric acid; ethylmagnesium bromide; hydrogen bromide; sodium hydride; acetic acid;
DOI:10.1021/jm00351a010

Reference yield:

: 82413-29-4
2-(3-Hydroxy-phenyl)-1-phenyl-butan-1-one

: 82413-24-9
3-{1-[1-[4-(2-Dimethylamino-ethoxy)-phenyl]-1-phenyl-meth-(Z)-ylidene]-propyl}-phenol

Guidance literature:: Multi-step reaction with 2 steps

1: 98percent H₂SO₄ / 12 h / Ambient temperature

2: 1.) C₂H₅MgBr, 3.) HCl

With hydrogenchloride; sulfuric acid; ethylmagnesium bromide;
DOI:10.1021/jm00351a010