1,3-Dioxolane, 2-methylene-4-phenyl-

Base Information

• Chemical Name: 1,3-Dioxolane, 2-methylene-4-phenyl-
• CAS No.: 82613-73-8
• Molecular Formula: C10H10O2
• Molecular Weight: 162.188
• DSSTox Substance ID: DTXSID00448726
• Nikkaji Number: J619.005G
• Mol file: 82613-73-8.mol

Synonyms:2-methylene-4-phenyl-1,3-dioxolane;82613-73-8;1,3-Dioxolane, 2-methylene-4-phenyl-;2-methylidene-4-phenyl-1,3-dioxolane;SCHEMBL4012071;DTXSID00448726

Chemical Property of 1,3-Dioxolane, 2-methylene-4-phenyl-

Chemical Property:

• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 162.068079557
• Heavy Atom Count: 12
• Complexity: 171

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=C1OCC(O1)C2=CC=CC=C2

Technology Process of 1,3-Dioxolane, 2-methylene-4-phenyl-

There total 4 articles about 1,3-Dioxolane, 2-methylene-4-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

2-bromomethyl-4-phenyl-1,3-dioxolane (124547-20-2) → 2-methylene-4-phenyl-1,3-dioxolane (82613-73-8)

Guidance literature:

With potassium tert-butylate; tetrabutylammomium bromide; at 75 ℃; for 0.0833333h; Product distribution; Irradiation; investigation of reactions of halogenated acetals;

DOI:10.1016/0040-4039(96)00110-4

Reference yield: 69.0%

2-chloromethyl-4-phenyl-1,3-dioxolane (82971-57-1) → 2-methylene-4-phenyl-1,3-dioxolane (82613-73-8)

Guidance literature:

With potassium tert-butylate; Aliquat 336; In tetrahydrofuran; at 20 ℃; Heating;

DOI:10.1021/jo990227g

Reference yield:

phenylethane 1,2-diol (93-56-1) → 2-methylene-4-phenyl-1,3-dioxolane (82613-73-8)

Guidance literature:

Multi-step reaction with 2 steps

1: toluene-4-sulfonic acid / 5 h / 115 °C

2: potassium tert-butylate / tetrahydrofuran / 5 h / 90 °C / Inert atmosphere

With potassium tert-butylate; toluene-4-sulfonic acid; In tetrahydrofuran;

DOI:10.1002/ange.202005114

upstream raw materials:

2-bromomethyl-4-phenyl-1,3-dioxolane

2-chloromethyl-4-phenyl-1,3-dioxolane

phenylethane 1,2-diol